吸入沙美特罗替卡松对哮喘儿童生长发育的影响
Effect of inhaled salmeterolticasone on cortisol and body mass in children with asthma
郑博娟1
作者信息
- 1. 河北省儿童医院呼吸四科,石家庄 050031
- 折叠
摘要
目的 探讨持续低剂量吸入沙美特罗替卡松对哮喘儿童血清皮质醇水平及体重的影响.方法 观察 25 例 4～11 岁轻中度哮喘治疗组儿童经沙美特罗替卡松治疗前、治疗半年及 1 年后的血清皮质醇、体重及增长变化,同 17 例对照组进行比较.结果 哮喘治疗组儿童血清皮质醇、体重及体重增长变化在治疗半年及 1 年后同对照组儿童相比差异均无统计学意义(P＞0.05).结论 持续低剂量吸入沙美特罗替卡松对哮喘儿童血清皮质醇、体重无明显影响,无体重过快增长.
Abstract
Objective To investigate the effect of continuous low-dose inhaled salmeterolticasone on serum cortisol level and the body mass of children with asthma.Methods Serum cortisol,the body mass and the body mass growth of 25 children with mild and moderate asthma aged 4 to 11 years were observed before treatment,6 months and 1 year after treatment with salmeterolticasone,compared with 17 children of the control group.Results There were no significant differences in serum cortisol,body mass and body mass increase between asthmatic children and the control group at 6 months and 1 year after treatment(P＞0.05).Conclusion Continuous low-dose inhaled salmeterolticasone has no significant effect on serum cortisol and the body mass of asthmatic children,and no excessive increase in body mass.
关键词
沙美特罗替卡松/哮喘/儿童/皮质醇/体重Key words
Salmeterolticasone/Asthma/Children/Cortisol/Body mass引用本文复制引用
基金项目
河北省卫生健康委员会项目(20190837)
出版年
2024
NETL
NSTL
万方数据