Clinical observation of aesculin digitalis eye drops combined with recombinant bovine basic fibroblast growth factor eye gel in the treatment of drug-induced dry eye in patients with glaucoma
Objective To investigate the clinical effect of aesculin digitalis eye drops combined with recombinant bovine basic fibroblast growth factor eye gel in the treatment of drug-induced dry eye in patients with glaucoma.Methods According to random number table method,60 patients with drug-induced dry eye with glaucoma admitted and diagnosed in a hospital from October 2020 to November 2023 were divided into the control group(recombinant bovine basic fibroblast growth factor eye gel,n=30)and the study group(recombinant bovine basic fibroblast growth factor eye gel+aesculin digitalis eye drops,n=30).To evaluate the difference of treatment effect,tear dynamics level,quality of life between the two groups.Results The total effective rate of the study group(96.67%)was higher than that of the control group(73.33%)(P<0.05).After 4 weeks of treatment,the indexes of tear dynamics and quality of life in the study group were better than those in the control group(P<0.05).Conclusion Aesculin digitalis eye drops combined with recombinant bovine basic fibroblast growth factor eye gel can effectively relieve the symptoms in the treatment of drug-induced dry eye in patients with glaucoma,improve the level of tear dynamics and improve the quality of life.
GlaucomaDrug-induced dry eyeAesculin digitalis eye dropsRecombinant bovine basic fibroblast growth factor eye gelThe level of tear dynamicsQuality of life