首页|造影随访前降支分叉病变边支应用不同PCI策略效果比较

造影随访前降支分叉病变边支应用不同PCI策略效果比较

扫码查看
目的 探讨药物涂层球囊联合药物洗脱支架在冠状动脉前降支分叉病变介入治疗中的应用价值。方法 选取2021年9月~2022年 6 月间蚌埠第三人民医院心内科收治的 30 例冠状动脉前降支分叉病变患者,随机分为药物洗脱支架(drug-eluting stent,DES)组和药物涂层球囊(drug-coated balloon,DCB)组。DES组采取分支病变常规球囊扩张后,行药物洗脱支架置入,而DCB组采取分支病变处理后,应用药物涂层球囊扩张,两组主支均行药物洗脱支架置入。比较两组术前、术后即刻及 6 个月后随访分支血管管腔直径变化。结果 两组间临床基本资料差异均无统计学意义(P>0。05);两组患者主支及分支管径组间差异无统计学意义(P>0。05);两组中主支术后即刻最小管径直径(minimal lumen diameter,MLD)及晚期管径丢失(late lumen loss,LLL)值差异均无统计学意义(P>0。05);对于分支情况,两组术后即刻MLD差异有统计学意义(P<0。05),术后 6 个月DCB组MLD与DES组差异无统计学意义(P>0。05),而DCB组LLL较DES组有所减少,差异有统计学意义(P<0。05)。结论 两组治疗均有效果,DES组术后即刻效果优于DCB组,而术后 6 个月显示DCB组LLL小于DES组,表明DCB能更好地防止晚期管径丢失。
To compare the effects of different percutaneous coronary intervention(PCI)strategies on the side branch of left anterior descending artery bifurcation lesions during angiographic follow-up
Objective To investigate the application value of drug-coated balloon combined with drug-eluting stent in interventional treatment of bifurcated anterior descending branch of coronary artery.Methods Thirty patients with anterior descending coronary artery bifurcation lesions admitted to the department of cardiology,the Third People's Hospital of Bengbu from September 2021 to June 2022 were randomly divided into drug-eluting stent(DES)group and drug-coated balloon(DCB)group.The DES group received conventional balloon dilatation for branch lesions and drug-eluting stent implantation,while the DCB group received drug-coated balloon dilatation for branch lesions and drug-eluting stent implantation for main branches in both groups.The changes of lumen diameter of branch vessels were compared between the two groups before operation,immediately and 6 months later.Results There was no significant difference in the basic clinical data between the two groups(P>0.05).There was no significant difference in the main branch and branch diameter between the two groups(P>0.05);There was no significant difference between the two groups in minimal lumen diameter(MLD)and late lumen loss(LLL)immediately after main branch surgery(P>0.05).There was a significant difference in MLD immediately after operation between the two groups(P<0.05);After 6 months there was no statistically significant difference of MLD between DCB and DES group(P>0.05),the LLL of DCB group is reduced compared to that of DES group,and the difference is statistically significant(P<0.05).Conclusion The immediate effect of DES group was better than that of DCB group,while the LLL of DCB group was lower than that of DES group 6 months after operation,indicating that DCB could better prevent late diameter loss.

Drug-coated balloonCoronary bifurcation diseasePercutaneous coronary intervention

刘俊杰

展开 >

蚌埠市第三人民医院心血管内科二病区,安徽蚌埠 233000

药物涂层球囊 冠脉分叉病变 经皮冠状动脉介入术

2024

中国处方药
南方医药经济研究所

中国处方药

影响因子:0.649
ISSN:1671-945X
年,卷(期):2024.22(8)