Investigation of antibiotics prophylaxis and influence factors of postoperative intracranial infection of a type I neurosurgical incision
Objective To investigate the use of antibiotics and postoperative intracranial infection in the perioperative period of a type I neurosurgical incision of a hospital.In order to improve the rational application level of antibiotics for perioperative prevention of type I incision,and provide basis for clinical intervention and monitoring in the hospital.Methods Extracted a total of 1 276 cases of patients undergoing type I incision neurosurgical in a neurosurgery,statistical analysis of neurosurgical type I incision of antibiotics prophylaxis and postoperative intracranial infection were undergoing with the unified method and standard.Results Among the 1 276 patients,the proportion of prophylactic antibiotics was 96.6%(1 232/1 276);the rational rate of antibiotics selection was 51.1%(629/1 232);the reasonable timing of dosing was 86.8%(1 069/1 232);the reasonable rate of surgery which should be appended was 23.4%(97/415);the ratio of course of treatment which≤24 h was 11.8%(145/1 232);the ratio of course of treatment which＞24 h and≤48 h was 2.2%(27/1 232);the ratio of course of treatment which＞48 h was 86.0%(1 060/1 232);the incidence of postoperative intracranial infection was 2.1%(27/1 276);the positive rate of bacterial culture was 40.7%(11/27);the results of single factor analysis showed:surgery time＞4 h,intraoperative blood loss＞750 ml,intracranial drainage tube time＞72 h were high risk factors for postoperative intracranial infection.Conclusion The proportion of prophylactic antibiotics in the perioperative period of neurosurgical type I incision of the hospital was high,and a low rational rate of antibiotic selection,a long course of antibiotic use,and a low reasonable rate of timing of administration and antibiotics which should be appended.It is suggested that the hospital should establish a risk factor score scale to predict the risk of postoperative intracranial infection according to the national perioperative antibiotic management rules,explore an effective and feasible management model,and improve the rational application level of antibiotics in perioperative period of neurosurgery.
NeurosurgeryType I incisionAntibioticsIntracranial infectionInfluence factors
万方数据
维普
