Cost-effectiveness analysis of dalteparin sodium injection and enoxaparin sodium injection in preventing venous thromboembolism after orthopedic surgery
Objective Analyze the cost-effectiveness of dalteparin sodium injection and enoxaparin sodium injection in preventing venous thromboembolism(VTE)in patients after orthopedic surgery,and provide economic basis for clinical medication decision-making.Methods The medical records of 106 patients with orthopaedic surgery who were admitted to Xindu District People's Hospital of Chengdu from July 2021 to December 2022 were retrospectively analyzed.According to different postoperative intervention methods,they were divided into two groups,the observation group and the control group,with 53 cases in each.The observation group received dalteparin sodium injection to prevent VTE after orthopedic surgery,while the control group received enoxaparin sodium injection for prevention.The cost-effectiveness of medication was then analyzed for both groups of patients.Results The cost of dalteparin sodium injection and enoxaparin sodium injection were 481.32 yuan and 616.42 yuan,respectively,and the preventive effective rates were 98.11%and 91.34%,respectively.There was no statistically significant difference in effectiveness and safety(P＞0.05),but the cost-effectiveness ratios of the two were 490.59 and 653.4,respectively.Conclusion The efficacy of using dalteparin sodium injection and enoxaparin sodium injection in preventing VTE after orthopedic surgery is equivalent,and both have high application value;However,in terms of drug treatment costs,dalteparin sodium injection has more economic advantages.
万方数据
维普
