Analysis of adverse reactions of piracetam injection based on real-world monitoring data
Objective To analyze the characteristics and influencing factors of adverse drug reactions(ADR)caused by piracetam injection,and the related risk factors of these adverse reactions,so as to provide reference for safe clinical medication.Methods ADR reports of piracetam injection in Hebei province from 2017 to 2022 were collected and analyzed retrospectively.Results Among the 1 012 ADR cases of piracetam injection,most of them were middle-aged and elderly patients(＞85%);the adverse drug reactions were mainly caused by high concentration of piracetam and sodium chloride injection(20%);the main system-organs involved were systemic damage(28.55%)and skin and accessory damage(24.31%).Conclusion Marketing authorization holder(MAH)should continue to strengthen post-marketing product monitoring,especially for the use of piracetam in elderly patients.Clinicians should strictly follow the instructions and closely monitor the occurrence of severe adverse reactions such as allergic shock.
Piracetam injectionAdverse drug reactionsRational drug useSafety
万方数据
维普
