Rationality analysis of the application of antitumor drugs in a hospital
Objective To analyze the irrational application of antitumor drugs in a hospital and the reasons for it,so as to provide references for the review of medical prescriptions by clinical pharmacists and the rational use of drugs in clinics.Methods 720 medical records containing antitumor drugs were randomly selected from the hospital for the whole year of 2023,and the antitumor drugs in them were reviewed,counted and analyzed.Results Among the 720 cases,65 had irrational medication,accounting for 9.03%of the total.The main manifestations were irrational pretreatment regimen(29.23%),inappropriate solvent(27.69%),inappropriate drug selection(16.92%),inappropriate order of administration(10.77%),inappropriate indication(6.15%),inappropriate dosage(4.62%),inappropriate chemotherapy regimen(3.08%),and contraindications to compounding(1.54%).Conclusion There was irrational use of antitumor drugs in the hospital.It was mainly manifested as irrational pretreatment program,inappropriate solvent,inappropriate drug selection and inappropriate order of administration,etc.The irrational use of drugs was mainly concentrated in chemotherapeutic drugs,followed by large molecule monoantibody drugs.Clinical pharmacists should strengthen the review of antitumor drugs and intervene in a timely manner to promote the rational use of drugs in the clinic and guarantee the safety of patients'medication.
Anti-tumor drugsRational use of drugsReview of medical prescription