首页|盐酸坦索罗辛缓释胶囊对输尿管体外冲击波碎石术后患者预后的影响

盐酸坦索罗辛缓释胶囊对输尿管体外冲击波碎石术后患者预后的影响

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目的 探究盐酸坦索罗辛缓释胶囊对输尿管体外冲击波碎石术后患者预后的影响。方法 按照随机数字表法将某院 2022 年 6月~2023 年 5 月期间纳入的输尿管体外冲击波碎石术后患者 60 例分为对照组(呋塞米治疗,n=30)和研究组(呋塞米片+盐酸坦索罗辛缓释胶囊联合治疗,n=30)。比较两组结石排出状况、肾功能、炎症反应、生活质量、不良事件发生情况等指标的变化差异,评估两组临床疗效。结果 相较于对照组(73。33%),研究组临床总有效率(96。67%)更高,差异有统计学意义(P<0。05);研究组结石排出状况各指标均优于对照组(P<0。05);治疗 3 周后研究组肾功能、炎症反应、生活质量各指标水平均优于对照组(P<0。05);相较于对照组(26。67%),研究组不良事件发生率(6。67%)更低(P<0。05)。结论 盐酸坦索罗辛缓释胶囊治疗输尿管体外冲击波碎石术后患者,其结石排出状况、肾功能、炎症反应、生活质量均得到改善,不良事件发生风险低,疗效显著。
Effect of tamsulosin hydrochloride sustained-release capsules on the prognosis of patients after ureteral extracorporeal shockwave lithotriptic surgery
Objective To explore the effect of tamsulosin hydrochloride sustained-release capsules on the prognosis of patients after ureteral extracorporeal shockwave lithotriptic surgery.Methods According to the random number table method,60 patients with ureteral extracorporeal shockwave lithotriptic surgery enrolled in a hospital from June 2022 to May 2023 were divided into the control group(furosemide treatment,n=30)and the study group(furosemide tablets+tamsulosin hydrochloride sustained-release capsules combined therapy,n=30).The change difference in the indicators of stone discharge status,renal function,inflammatory response,quality of life,adverse events between the two groups were compared,and the clinical efficacy of the two groups were evaluated.Results Compared with the control group(73.33%),the total clinical effective rate of the study group(96.67%)was higher(P<0.05).The indexes of stone discharge status in the study group were better than those in the control group(P<0.05).After 3 weeks of treatment,renal function,inflammation and quality of life in the study group were better than those in the control group(P<0.05).Compared with the control group(26.67%),the incidence of adverse events in the study group(6.67%)was lower(P<0.05).Conclusion Using tamsulosin hydrochloride sustained release capsules in patients after ureteral extracorporeal shockwave lithotripsy can improve stone discharge status,renal function,inflammatory response and quality of life,with low risk of adverse events and significant curative effect.

Tamsulosin hydrochloride sustained-release capsulesUreteral calculiExtracorporeal shockwave lithotripsyRenal functionInflammatory responseQuality of lifeOccurrence of adverse events

张冲、唐飞、朱文尧

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蚌埠市第三人民医院泌尿外科,安徽 蚌埠 233099

盐酸坦索罗辛缓释胶囊 输尿管结石 体外冲击波碎石 肾功能 炎症反应 生活质量 不良事件发生情况

2024

中国处方药
南方医药经济研究所

中国处方药

影响因子:0.649
ISSN:1671-945X
年,卷(期):2024.22(10)