首页|特拉唑嗪联合硝苯地平控释片对高血压脑出血患者血压水平的影响

特拉唑嗪联合硝苯地平控释片对高血压脑出血患者血压水平的影响

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目的 研究特拉唑嗪联合硝苯地平控释片对高血压脑出血患者血压水平的影响。方法 选取 2019 年 1 月~2023 年 12 月在肇庆市第二人民医院治疗的 102 例高血压脑出血患者作回顾性分析。对照组 50 例采用常规治疗联合苯磺酸氨氯地平治疗;研究组 52 例使用特拉唑嗪联合硝苯地平控释片治疗。比较两组治疗后情况。结果 研究组总有效率高于对照组(P<0。05);与治疗前相比,治疗后研究组白昼收缩压(dSBP)、白昼舒张压(dDBP)、夜间收缩压(nSBP)及夜间舒张压(nDBP)水平均低于对照组(P<0。05);研究组再次脑出血的发生率低于对照组(P<0。05);用药后两组血糖及肝肾功能等指标无明显异常变化,未出现不良事件,两组安全性相当。结论 特拉唑嗪联合硝苯地平控释片可稳定高血压脑出血患者的血压水平,减少再次脑出血的风险,保障患者的用药安全性。
Effect of terazosin combined with nifedipine controlled release tablets on blood pressure levels in patients with hypertensive intracerebral hemorrhage
Objective To study the effect of trazosin combined with nifedipine controlled release tablets on blood pressure levels in patients with hypertensive cerebral hemorrhage.Methods A retrospective analysis was performed on 102 patients with hypertensive cerebral hemorrhage treated in the Second People's Hospital of Zhaoqing City from January 2019 to December 2023.In the control group,50 cases received conventional treatment combined with amlodipine phenylate theatment;in the study group,52 patients were treated with terazosin combined with nifedipine controlled release tablets.Condition of the two groups were compared after treatment combined with omlodipine phenylate theatment.Results The total effective rate of the study group was higher than that of the control group(P<0.05).Compared to before treatment,,the levels of daytime systolic blood pressure(dSBP),daytime diastolic blood pressure(dDBP),nighttime systolic blood pressure(nSBP)and nighttime diastolic blood pressure(nDBP)in the study group were lower than those in the control group after treatment(P<0.05);The incidence of recurrent intracerebral hemorrhage in the study group was lower than that in the control group(P<0.05).There were no significant abnormal changes in blood glucose,liver and kidney function indexes in the two groups after treatment.And the safety of the two groups was comparable.Conclusion Terazosin combined with nifedipine controlled release tablets can stabilize the blood pressure levels of patients with hypertensive cerebral hemorrhage,reduce the risk of recurrent intracerebral hemorrhage,and ensure the safety of patient medication.

TerazosinNifedipine controlled release tabletHypertensive cerebral hemorrhageBlood pressure levelRisk of recurrent intracerebral hemorrhage

陈桂坚、方凯、钟日君、陈文焰

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肇庆市第二人民医院神经外科,广东 肇庆 526020

特拉唑嗪 硝苯地平控释片 高血压脑出血 血压水平 再次脑出血风险

2024

中国处方药
南方医药经济研究所

中国处方药

影响因子:0.649
ISSN:1671-945X
年,卷(期):2024.22(10)