自体富血小板血浆椎间盘内注射治疗椎间盘源性腰痛的疗效
Efficacy of autologous platelet-rich plasma intradiscal injection in the treatment of discogenic low back pain
帅明 1何成 2赵岚 2双峰 2姜文华 2王超 2胡文文 2李浩2
作者信息
- 1. 联勤保障部队第九○八医院骨科,江西南昌 330002;崇义县人民医院骨科,江西赣州 341399
- 2. 联勤保障部队第九○八医院骨科,江西南昌 330002
- 折叠
摘要
目的 探讨自体富血小板血浆(PRP)椎间盘内注射对椎间盘源性腰痛(DLBP)的治疗效果.方法 回顾性分析2022年1月至2023年6月于联勤保障部队第九○八医院就诊的47例DLBP患者的临床资料.根据治疗方法分为PRP联合塞来昔布胶囊治疗组(试验组)16例和单纯塞来昔布胶囊治疗组(对照组)31例.统计治疗前、治疗后1周、治疗后1个月及6个月的腰痛视觉模拟评分(VAS)及Oswestry功能障碍指数(ODI).结果 随着治疗时间的推移,试验组VAS、ODI评分逐渐降低;对照组治疗后1周的VAS、ODI评分较治疗前降低,之后呈现逐渐上升趋势;试验组治疗后1个月、治疗后6个月VAS评分及ODI评分低于对照组(P＜0.05).结论 自体PRP联合塞来昔布胶囊治疗DLBP远期疗效要优于单纯口服塞来昔布胶囊,可作为DLBP的一种有效治疗方式.
Abstract
Objective To investigate the efficacy of intradiscal injection of autologous platelet-rich plasma(PRP)in the treatment of discogenic low back pain(DLBP).Methods A retrospective analysis of clinical data from 47 DLBP patients treated at No.908 Hospital of Joint Logistics Support Force from January 2022 to June 2023 was conducted.Patients were divided into a PRP combined with celecoxib capsule treatment group(experimental group,n=16)and a celecoxib capsule monotherapy group(control group,n=31)based on the treatment method.The visual analogue scale(VAS)of low back pain and Oswestry disability index(ODI)scores were recorded before treatment,at 1 week,1 month,and 6 months after treatment.Results VAS scores and ODI scores in the experimental group gradually decreased over time;the VAS scores and ODI scores in the control group decreased at 1 week after treatment compared to before treatment,but then showed a gradual upward trend.The VAS scores and ODI scores in the experimental group were lower than those in the control group at 1 month and 6 months after treatment(P＜0.05).Conclusion The long-term efficacy of autologous PRP combined with celecoxib capsule in treating DLBP is superior to that of celecoxib capsule monotherapy and can be considered as an effective treatment for DLBP.
关键词
富血小板血浆/椎间盘源性腰痛/塞来昔布/椎间盘内注射Key words
Platelet-rich plasma/Discogenic low back pain/Celecoxib/Intradiscal injection引用本文复制引用
基金项目
江西省卫生健康委科技项目(202210458)
出版年
2024
NETL
NSTL
万方数据