摘要
目的 调查河北省儿童医院住院儿童传染性单核细胞增多症(IM)的流行病学特征.方法 从2019年1月1日至2022年12月31日来自河北省儿童医院的出院病历首页,提取包括性别、年龄、住院花费和住院天数等医疗信息进行分析.结果 共有1 043例IM病例,占所有住院患儿的0.53％(1 043/197 706),男女比例为1.56:1.所有住院IM患儿住院天数为9(7,11)d,1 043例中来自城市和农村地区的分别占41.42％和58.58％,差异无统计学意义(P＞0.05).住院费用为8 065(715.60,1 343.29)元.＜1岁、1～3岁、4～6岁、7～12岁和13～18岁IM患儿占总住院患儿的比例分别为0.05％、0.76％、0.94％、0.32％和0.12％,差异有统计学意义(x2=445.580,P＜0.01),其中4～6岁IM患儿的比例最高.2019、2020、2021、2022年IM患儿占总住院患儿的比例依次为0.66％、0.74％、0.61％、0.11％,差异有统计学意义(x2=232.145,P＜0.01),其呈先上升后下降,以2020年最高.此外7月至9月IM住院例数达峰,而12月至3月最低.肝功能异常、支气管炎和肺炎是住院IM患儿常见的并发症.结论 在住院患儿中,IM的流行具有年龄和季节性特征,应采取措施降低儿童IM发病率,减少其疾病负担和并发症.
Abstract
Objective To investigate the epidemiological characteristics of infectious mononucleosis(IM)among hospitalized children in Hebei Children's Hospital.Methods From January 1,2019 to December 31,2022,medical information including gender,age,hospitalization cost,and hospital stay were extracted from the first page of the discharge medical record from Hebei Children's Hospital for analysis.Results A total of 1 043 IM cases were identified,accounting for 0.53％(1 043/197 706)of all hospitalized cases,and the male-to-female ratio was 1.56:1.The hospital stay for all IM cases was 9(7,11)days,and 41.42％and 58.58％of the 1 043 children were from urban and rural areas,respectively,with no statistically significant(P＞0.05).The hospitalization cost was 8 065(715.60,1 343.29)yuan.The proportion of IM children in all hospitalized children aged＜1,1-3,4-6,7-12 and 13-18 years old were 0.05％,0.76％,0.94％,0.32％and 0.12％,respectively,and the difference was statistically significant(x2=445.580,P＜0.01),with the highest in aged 4-6 years old.The proportion of IM children in all hospitalized children in 2019,2020,2021 and 2022 were 0.66％,0.74％,0.61％and 0.11％,respectively,with a statistically significant difference(x2=232.145,P＜0.01),which increased first and then decreased,with the highest in 2020.In addition,the number of IM hospitalization reached the peak from July to September and the lowest from December to March.Common complications of hospitalized IM children included liver function abnormalities,bronchitis,and pneumonia.Conclusion The prevalence of IM in hospitalized children is characterized by age and seasonality,and measures should be taken to reduce the incidence of IM in children,and to reduce their disease burden and complications.
基金项目
河北省医学科学研究重点课题计划项目(20200670)
NETL
NSTL
万方数据