Esketamine is an N-methyl-D-aspartic acid(NMDA)receptor antagonist,which has a better effect than ketamine in anesthesia.Esketamine can act on the nervous system,respiratory system,circulatory system,etc.Due to its fast onset and rapid metabolism,it has unique advantages in anesthesia management.Esketamine can not only be used alone in short-term anesthesia operations,but also in combination with various anesthetic drugs,providing a new choice for anesthesia management in various clinical surgeries and outpatient examinations.