瑞马唑仑在特殊患者围术期应用的进展
Perioperative application of remimazolam in specific patients
李博文 1王浩然 1杨春 1刘存明1
作者信息
- 1. 南京医科大学第一附属医院麻醉与围术期医学科,江苏南京 210029
- 折叠
摘要
瑞马唑仑是一种新型的超短效苯二氮类镇静催眠药,主要经肝脏非特异性酯酶代谢,具有对血流动力学和呼吸功能影响小、可控性强、代谢迅速、长时间使用无药物蓄积、苏醒迅速等优点,且有特异性拮抗药氟马西尼,目前已被用于多种环境下的麻醉镇静.本文就瑞马唑仑在老年、肝肾功能不全、儿童、肥胖和产科患者麻醉中的应用进行综述,旨在为临床合理使用提供参考.
Abstract
Remimazolam is a novel ultrashort-acting sedative-hypnotics of benzodiazepines,which metabolized by tissue non-specific cholinesterase.It has the character that hardly influence on hemodynamics and respiratory function.With rapid metabolism,it has a strong controllability and doesn't accumulation after long-time infusion.Moreover,it provides a rapid recovery after anesthesia that can be antagonized by flumazenil specifically.Nowadays,remimazolam is used in procedure sedation in numerous situations of anesthesia.This article focuses on elderly,hepatic and renal impairment,pediatrics,obesity,and obstetrics patients,aims at providing references in clinical applications.
关键词
瑞马唑仑/老年/肝功能不全/肾功能不全/儿童/肥胖/产科Key words
Remimazolam/Elderly/Hepatic impairment/Renal impairment/Children/Obesity/Obstetrics引用本文复制引用
出版年
2024
NETL
NSTL
万方数据