艾司氯胺酮对肝脏缺血再灌注损伤的保护作用
Protective effect of esketamine on hepatic ischemia-reperfusion injury
杜书垚 1吕靖 1周子愉 1冯光武 1罗向红1
作者信息
- 1. 湖北医药学院附属太和医院麻醉科,湖北十堰 442000
- 折叠
摘要
艾司氯胺酮作为一种围术期的镇静、镇痛药物,已在欧美国家得到广泛应用.但艾司氯胺酮在围术期对于肝脏的保护作用仍在应用研究阶段.本文简要介绍了艾司氯胺酮药物,对其在肝脏缺血再灌注中的功效、作用机制以及研究进展进行了相关阐述,以给此相关领域的临床工作人员提供用药参考.
Abstract
Esketamine,as a perioperative sedative and analgesic drug,has been widely used in Europe and America.However,the protective effect of esketamine on the liver during the perioperative period is still in the applicated research stage.This article briefly introduces the efficacy,mechanism of action,and research progress of esketamine in hepatic ischemia-reperfusion,in order to provide a medication reference for clinical staff in this field.
关键词
艾司氯胺酮/肝脏缺血再灌注损伤/细胞凋亡/细胞焦亡/铁死亡Key words
Esketamine/Hepatic ischemia-reperfusion injury/Apoptosis/Pyroptosis/Ferroptosis引用本文复制引用
出版年
2024
NETL
NSTL
万方数据