摘要
寄生虫病在反刍动物中广泛流行,给畜牧业造成了严重损失,临床通常使用化学疗法来防治.但由于抗寄生虫药物的不合理使用,导致耐药性问题在畜牧业中愈发严重,给公共卫生安全和反刍动物养殖业健康发展带来了极大的挑战.选用高效、广谱、低毒、投药方便、价格低廉、低残留和不易产生耐药性的抗寄生虫药是治疗动物寄虫病的基础,而通过联合用药、穿梭用药和轮换用药的方式,可维持和延长驱虫药的药效.文章基于世界各地反刍动物蠕虫病的现有流行病学研究,分析了反刍动物蠕虫病的流行现状、危害以及抗蠕虫药的应用现状与发展趋势,为反刍动物蠕虫病的药物研发提供参考.
Abstract
Parasitic infections are widely prevalent in ruminants,causing serious losses to animal husbandry,and people usually use chemotherapy to prevent and control them.However,due to the unreasonable use of insecticides,the problem of insecticide resistance(AR)has become increasingly serious in animal husbandry,posing great challenges to public health safety and the healthy development of ruminant breeding.The selection of highly efficient,broad-spectrum,low toxicity,convenient administration,low price,low residue,and resistant antiparasitic drugs is the founda-tion for treating animal helminthiasis.By combining,shuttle,and rotating medication,the efficacy of antiparasitic drugs can be maintained and extended.This article was based on existing epidemiological studies on ruminant helminthiasis around the world,discussing the epidemic status and harm of ruminant helminthiasis,as well as the current status and development trends of anti worm drugs,providing insights for drug research and development of ruminant helminthiasis.
国家科技期刊平台
NSTL
维普
万方数据