Research Progress on Structural Variation of Yak Genome
Genomic structural variation(SV)typically refers to the forms of variation within the genome that affect the direction or length of DNA sequences,including deletions,insertions,duplications,translocations,and inversions.SV directly or indirectly affects gene expression through gene dose and position effects,leading to phenotypic variation in species.In the past decade,with the rapid development of whole genome resequencing technology and high-density chip technology,significant progress has been made in the research of yak genome SV.This article elaborated on the types,formation mechanisms,and detection methods of genomic SV,and reviewed the research status of yak genomic SV in the past 10 years,with the aim of providing reference for in-depth research on yak genomics and accelerating the molecular breeding process of yaks.
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维普
