Association of MEF2A Gene Copy Number Variation with Growth Traits in Ashidan Yak
In order to explore the effect of MEF2A gene copy number variation on the growth traits of Ashidan yak,body weight,withers height,body length and chest girth of 92 Ashidan yaks at 6,12,18 and 30 months of age were mea-sured.The relative expression of MEF2A gene was detected by qPCR,and the correlation analysis was carried out by SPSS software.The results showed copy number variation of MEF2A gene was significantly correlated with the chest girth of 18 months Ashidan yak(P<0.01)and the body length of 6 months Ashidan yak(P<0.01),and was significantly correlated with the withers height of 18 months Ashidan yak(P<0.05).At the same time,multiple comparisons showed that the 6-month-old body length of normal type in Ashidan yak was significantly higher than the other two types(P<0.01),the 18-month-old withers height of normal type was significantly lower than the gain type(P<0.05),and the chest girth of loss type and normal type were significantly higher than the gain type(P<0.01).The expression of MEF2A gene in Ashidan yak muscle tissue was significantly higher than that in other tissues(P<0.01).In summary,copy number variation of MEF2Agene can affect the growth and development of Ashidan yak.
Ashidan yakMEF2Agenecopy number variationgrowth traitsassociation analysis