The Correlation Analysis of Clinical and MRI/MRV Characteristics with Anticoagulant Therapy Prognosis in Patients with Cerebral Venous Sinus Thrombosis
Objective To explore the evaluation indicators of MRI combined with MRV and related clinical features in predicting different prognosis of patients with cerebral venous sinus thrombosis after anticoagulation treatment;Guide clinical early intervention and treatment to improve patient prognosis.Methods Clinical and imaging data of 47 patients with cerebral venous sinus thrombosis diagnosed by MRI combined with MRV at the Affiliated Hospital of Xuzhou Medical University from January 2017 to February 2023 were collected.The causes,clinical features,and imaging features of MRI and MRV that affect the prognosis of anticoagulation therapy in CVST patients were retrospectively analyzed.Results Univariate analysis revealed significant age differences(P=0.014),D-dimer levels(P=0.039),venous infarction with bleeding(P=0.044),focal neurological deficits(P=0.002),and collateral circulation(P=0.014)across various prognostic groups.Multifactorial binary logistic regression analysis showed that focal neurologic deficit(OR=58.138,95％CI:1.423-2374.543,P=0.032)was an independent risk factor for poor short-term prognosis in CVST patients,and collateral circulation grade 1(OR=0.008,95％CI:0.000-0.807,P=0.040)was a protective factor for good prognosis.Conclusion Focal neurological impairment is an autonomous risk aspect for adverse short-term prognosis among patients with CVST,and collateral circulation level 1 is independently associated with good prognosis in CVST patients.
NETL
NSTL
万方数据
维普
