Textural Features on Magnetic Resonance Imaging in IDH1 Mutant Glioblastoma
Objective To investigate the texture on Magnetic Resonance Imaging and prognosis in isocitratedehydrogenase-1(IDH1)mutant glioblastoma.MethodsA total of 118 GBM were included by the pathological diagnosis.31 texture of MRI were extracted from 3D slicer.Using SPSS 22.0 analysis software,the x 2 test,Student's t-test and Mann-Whitney U-test were conducted to analysis the relationship between the status of IDH1and MRI textural features in GBM.ResultsThe IDH1 mutant GBM was compared with IDH1 wild-type GBM,there were 18 of Magnetic resonance textural features which were significantly different,including Run Percentage(RP)、Surface:Volume Ratio、Energy、Entropy、Uniformity、Auto-correlation、Cluster Prominence、Cluster Tendency、Difference Entropy、Energy:Gray Level Co Occurrence Matrix(GLCM)、Entropy:Gray Level Co Occurrence Matrix(GLCM)、Homogeneity 1、Sum Average、Sum Entropy、Sum Variance、Variance:Gray Level Co Occurrence Matrix(GLCM)、GLN、Cluster Shade.Conclusion IDH1 mutant GBM were compared with IDH1 wild-type GBM,there were significantly different about 18 MRI textural features.
GlioblastomaThe Status of IDH1Textural Feature on Magnetic Resonance ImagingPrognosis