Analysis of the Changes in SPECT/CT Imaging Features and Diagnostic Value of Skull Base Bone Metastasis in Nasopharyngeal Carcinoma
Objective To analyze the application value of single photon emission computed tomography(SPECT/CT)in the diagnosis of skull base metastasis in nasopharyngeal carcinoma(NPC).Methods Sixty NPC patients who were scheduled to undergo surgical treatment in our hospital from June 2019 to September 2021 were selected.All patients underwent preoperative SPECT/CT and magnetic resonance imaging(MRI)examinations,with histopathological examination as the"gold standard".The imaging features of SPECT/CT and MRI examinations were compared and analyzed,as well as the diagnostic Results and diagnostic efficacy of SPECT/CT and MRI examinations for NPC skull base bone metastasis.The accuracy,sensitivity,specificity,positive predictive value,and negative predictive value of NPC evaluated by SPECT/CT were 81.66％,86.04％,70.58％,88.09％,and 66.66％,respectively.The accuracy,sensitivity,specificity,positive predictive value,and negative predictive value of MRI were 63.33％,67.44％,52.94％,78.37％,and 39.13％,respectively(P＜0.05);The accuracy,sensitivity,specificity,positive predictive value,and negative predictive value of NPC skull base bone metastasis evaluated by SPECT/CT were 76.66％,73.60％,81.81％,87.50％,and 64.28％,respectively.The accuracy,sensitivity,specificity,positive predictive value,and negative predictive value of MRI were 56.66％,50.00％,68.18％,73.07％,and 44.11％,respectively(P＜0.05).Conclusion SPECT/CT has high diagnostic value in NPC skull base bone metastases.Clinical reference to SPECT/CT imaging features before radiotherapy can comprehensively grasp the lesion situation and improve diagnostic accuracy.
Nasopharyngeal CancerSkull Base Bone MetastasisSingle Photon Emission Computed TomographyTracerImage Features
NETL
NSTL
万方数据
维普
