摘要
目的 分析单光子发射计算机体层成像CT(SPECT/CT)在诊断鼻咽癌(NPC)颅底骨转移瘤中的应用价值.方法 选取2019年1月-2021年6月期间于我院拟接受手术治疗的60例NPC患者,全部患者术前均接受SPECT/CT及核磁共振成像(MRI)检查,以随访作为"金标准",对比分析患者SPECT/CT、MRI检查影像特征以及SPECT/CT、MRI检查对NPC颅底骨转移的诊断结果和诊断效能.结果 经SPECT/CT检查评估NPC的准确度、灵敏度、特异度、阳性预测值、阴性预测值分别为81.66％、86.04％、70.58％、88.09％、66.66％,经MRI检查准确度、灵敏度、特异度、阳性预测值、阴性预测值分别为63.33％、67.44％、52.94％、78.37％、39.13％(P＜0.05);经SPECT/CT检查评估NPC颅底骨转移的准确度、灵敏度、特异度、阳性预测值、阴性预测值分别为76.66％、73.60％、81.81％、87.50％、64.28％,经MRI检查准确度、灵敏度、特异度、阳性预测值、阴性预测值分别为56.66％、50.00％、68.18％、73.07％、44.11％(P＜0.05).结论 SPECT/CT在NPC颅底骨转移瘤中有较高的诊断价值,临床在放射治疗前参照SPECT/CT影像特征,可全面掌握病灶情况,提高诊断的准确率.
Abstract
Objective To analyze the application value of single photon emission computed tomography(SPECT/CT)in the diagnosis of skull base metastasis in nasopharyngeal carcinoma(NPC).Methods Sixty NPC patients who were scheduled to undergo surgical treatment in our hospital from June 2019 to September 2021 were selected.All patients underwent preoperative SPECT/CT and magnetic resonance imaging(MRI)examinations,with histopathological examination as the"gold standard".The imaging features of SPECT/CT and MRI examinations were compared and analyzed,as well as the diagnostic Results and diagnostic efficacy of SPECT/CT and MRI examinations for NPC skull base bone metastasis.The accuracy,sensitivity,specificity,positive predictive value,and negative predictive value of NPC evaluated by SPECT/CT were 81.66％,86.04％,70.58％,88.09％,and 66.66％,respectively.The accuracy,sensitivity,specificity,positive predictive value,and negative predictive value of MRI were 63.33％,67.44％,52.94％,78.37％,and 39.13％,respectively(P＜0.05);The accuracy,sensitivity,specificity,positive predictive value,and negative predictive value of NPC skull base bone metastasis evaluated by SPECT/CT were 76.66％,73.60％,81.81％,87.50％,and 64.28％,respectively.The accuracy,sensitivity,specificity,positive predictive value,and negative predictive value of MRI were 56.66％,50.00％,68.18％,73.07％,and 44.11％,respectively(P＜0.05).Conclusion SPECT/CT has high diagnostic value in NPC skull base bone metastases.Clinical reference to SPECT/CT imaging features before radiotherapy can comprehensively grasp the lesion situation and improve diagnostic accuracy.
基金项目
广东省医学科学技术研究基金项目(A201810117)
NETL
NSTL
维普
万方数据