The Diagnostic Value of CT Angiography Combine with Serum Urea,Cystatin C,and Triglyceride Glucose Product Index in the Degree Of Coronary Artery Stenosis and the Relationship between Plaque Properties in Patients with Coronary Heart Disease
Objective To explore the relationship between the diagnostic value of CT angiography(CTA)combine with serum uric acid(UA),cystatin C(Cys C),and triglyceride glucose product(TyG)index in the degree of coronary artery stenosis(hereinafter referred to as coronary artery stenosis)and plaque properties in patients with coronary heart disease(CHD).Methods A total of 129 CHD patients who were admitted to our hospital from February 2021 to February 2023 were selected.All patients underwent CTA examination to obtain parameters such as vascular volume,plaque volume,reconstruction index(RI),and plaque load.Serum UA,Cys C,triglycerides,and fasting blood glucose levels were measured,and the TyG index was calculated.CHD patients were divided into moderate stenosis group and severe stenosis group,calcified plaque group and non calcified plaque group based on the degree of coronary stenosis and plaque nature.The differences in CTA parameters and serum UA,Cys C,and TyG indices among CHD patients with different degrees of coronary stenosis and plaque properties were compared.The diagnostic value of combining CTA parameters with serum UA,Cys C,and TyG indices for the degree of coronary artery stenosis through the analysis of subject operating characteristics(ROC)curve.Results The blood vessel volume of the CHD group was smaller than that of the control group(P＜0.05),and the plaque load,degree of vascular stenosis,Rl,CTA parameter model CTA',serum UA,Cys C,and TyG index were higher than those of the control group(P＜0.05).The plaque load,vascular stenosis degree,Rl,CTA parameter model CTA'and serum UA,Cys C,and TyG index in the severe stenosis group were higher than those in the moderate stenosis group(P＜0.05),while the plaque load,Rl,and serum UA,Cys C,and TyG index in the non calcified plaque group were higher than those in the calcified plaque group(P＜0.05).When using CTA parameters(CTA'),serum UA,Cys C,and TyG index alone or in combination,ROC-AUC(0.95CI)was 0.767(0.568～0.954),0.703(0.432～0.963),0.732(0.524～0.918),0.741(0.560～0.914),and 0.891(0.773～0.983),respectively.Joint application has higher diagnostic efficiency.Conclusion In CHD patients,the vascular volume decreases,plaque load,degree of vascular stenosis,Rl increases,and serum UA,Cys-C,and TyG indices all increase,which are relate to the formation of calcified plaques.CTA,serum UA,Cys C,and TyG index can all diagnose the degree of coronary artery stenosis,and the combined diagnostic efficacy is higher.
Coronary Heart DiseaseDegree of Coronary Artery StenosisPatch PropertiesCT AngiographyUric AcidCystatin CTriglyceride Glucose Product Index
NETL
NSTL
万方数据
维普
