Correlation Analysis of IVIM-DWI and Multilayer Spiral CT with Microvascular Invasion in Hepatocellular Hepatocellular Carcinoma
Objective To investigate the correlation analysis between in voxel incoherent motion diffusion-weighted imaging(IVIM-DWI)multilayer spiral CT(MSCT)and microvascular invasion(MVI)in hepatocellular hepatocellular carcinoma(HCC).Methods The clinical data of 100 patients with HCC admitted to our hospital from December 2019 to December 2022 were selected for retrospective analysis.All patients underwent pathological examination,VIM-DWI examination and MSCT examination.100 patients were diagnosed as MVI positive in 38 cases and MVI negative in 62 cases by surgical pathology.The differences in the analysis of qualitative and quantitative parameters of IVIM-DWI and MSCT between the two groups were compared,and the diagnostic value of quantitative parameters of IVIM-DWI,quantitative parameters of MSCT and combined data for the presence of MVI in HCC was analyzed by ROC curve.Results The MVI-positive group had higher marginal grossness,peritumoral low signal,peritumoral enhancement,and presence of halo sign than the MVI-negative group(P<0.05),and lower tumor envelope than the MVI-negative group(P<0.05).There was no statistically significant difference between the two groups in D*and F(P>0.05),but ADC and D were lower in the MVI-positive group than in the MVI-negative group(P<0.05).CT values in the arterial phase were lower in the MVI-positive group than in the MVI-negative group(P<0.05),and CT values in the delayed phase,CT values in the portal phase,and tumor size were higher than in the MVI-negative group(P<0.05).analysis of ROC curves showed that The AUCs of ADC,D,D*,f,delayed phase CT value,portal vein phase CT value,arterial phase CT value,and tumor size for diagnosing HCC with MVI were 0.775,0.856,0.609,0.565,0.708,0.728,0.643,and 0.705,respectively.MSCT parameters,IVIM-DWI parameters,and combined data for diagnosing HCC The AUCs for the presence of MVI were 0.809,0.832,and 0.920,respectively,all with good accuracy.Conclusion IVIM-DWI and MSCT qualitative and quantitative parameters were correlated with MVI in HCC patients,while both IVIM-DWI and MSCT had some value in diagnosing MVI,and the combined diagnosis was more accurate.