绝经后女性急性骨质疏松性骨折与腰部椎旁肌肉CT定量的相关性
Correlation between CT Measurement Parameters of Lumbar Paravertebral Muscles in Postmenopausal Acute Osteoporotic Spinal Compression Fractures
李雨蒙 1朱文玲 1谢智雯 1陈新蕾 1赵倩 1李绍东 1张秀莉1
作者信息
- 1. 徐州医科大学附属医院影像科(江苏徐州 221000)
- 折叠
摘要
目的 采用CT定量测量绝经后女性腰部椎旁肌肉脂肪浸润程度并探讨其与急性骨质疏松性椎体骨折(OVF)发生的相关性.方法 回顾性分析绝经后女性中85例急性OVF及同期94例无OVF的骨质疏松患者(对照组)的临床资料及CT定量测量资料.采用组内相关性检验(ICC检验)分别评估2名影像医师对椎旁肌相关参数测量的一致性,采用x 2检验、t检验及Logistic回归分析急性OVF与椎旁肌的相关性,采用受试者工作特征(ROC)曲线分析各独立影响因素预测绝经后妇女急性骨质疏松性压缩性骨折的效能.结果 (1)2名影像医师对椎旁肌定量测量数据(ICC均＞0.875)具有较高一致性.(2)两组患者的年龄、L1椎体最大矢状径、横截面积(CSAL1/2)、相对横截面积(rCSAT12/L1、L1/2、L4/5、L5/S1)、脂肪浸润程度(FIT12/L1、L1/2、L4/5、L5/S1)差异有统计学意义(P均＜0.05).(3)二元多因素Logistic回归分析结果显示rCSAL1/2、FIT12/L1是OVF的独立影响因素(P均＜0.05).(4)rCSAL1/2、FIT12/L1受试者工作特征曲线(ROC)的曲线下面积(AUC)分别为0.823、0.852.结论 rCSAL1/2是OVF的独立保护因素,FIT12/L1是OVF的独立危险因素.
Abstract
Objective To measure the parameters of lumbar paravertebral muscle degeneration in postmenopausal women acute osteoporotic spinal compression fractures and to explore their correlation with osteoporotic vertebral fractures.Methods The clinical baseline data and CT quantitative measurement data of postmenopausal 84 patients with OVF and 86 patients without OVF(control group)were analyzed retrospectively.Intraclass correlation coeficient(ICC)was used to evaluate the consistency of the parameters of lumbar paravertebral muscle by two radiologists.x 2 test,independent sample t test,and Logistic regression analysis were used to analyze the relationship between acute OVF and lumbar paravertebral muscle.The receiver operating characteristic(ROC)curve was used to analyze the independent influencing factors and predict the efficacy of postmenopausal women acute osteoporotic spinal compression fractures.Results(1)Two radiologists had high consistency in the measurement of CT quantitative measurement data(ICC＞0.875).(2)There were significant differences between age,the largest coronary and sagittal diameter of L1 vertebral body,CSAL1/2,rCSAT12/L1、L1/2、L4/5、L5/s1,FIT12/L1、L1/2、L4/5、L5/s1(P＜0.05).(3)Binary multivariate logistic regression analysis showed rCSAL1/2,FIT12/L1 were independent influencing factors of OVF.(4)The area under the curve of rCSAL1/2 and FIT12/L1 were 0.823、0.852.Conclusion rCSAL1/2 is an independent protective factor for OVF,while FIT12/L1 are independent risk factors for OVF.
关键词
骨质疏松性椎体骨折/椎旁肌/脂肪浸润Key words
Osteoporotic Vertebral Fractures/Lumbar Paravertebral Muscle/Fat Infiltration引用本文复制引用
基金项目
国家自然科学基金面上项目(82271980)
出版年
2024
NETL
NSTL
维普
万方数据