Diagnostic Value of Quantitative MSCT Parameters for the Characterization of Giant Cell Tumor of Bone and the Relationship with Clinical Prognosis
Objective To investigate the diagnostic value of quantitative parameters of multilayer spiral CT-enhanced scanning(MSCT)for the characterization of giant cell tumor of bone and the relationship with clinical prognosis.Methods Eighty patients with giant cell tumor of bone in our hospital from January 2019 to January 2021 were selected as the observation group,and another 80 patients with hemolytic tumor or tumorigenic lesions who were not giant cell tumor of bone admitted in the same period were selected as the control group.To compare the quantitative parameters of MSCT between the two groups and analyze the diagnostic value of quantitative parameters of MSCT for the characterization of giant cell tumor of bone;to compare the clinical data and quantitative parameters of MSCT of patients with different prognosis,to analyze the relationship between quantitative parameters of MSCT and clinicopathological characteristics of patients with giant cell tumor of bone,and the factors influencing the clinical prognosis of patients with giant cell tumor of bone.Results Compared with the preenhancement plain CT values,the postenhancement CT values of both groups were significantly higher,and the difference was statistically significant(P＜0.05);the preenhancement plain CT values,postenhancement CT values and CT increase values of the observation group were significantly higher than those of the control group,and the difference was statistically significant(P＜0.05).Plotting the subject operating characteristic(ROC)curves for the diagnosis of giant cell tumor of bone with preenhanced plain CT value,postenhanced CT value and CT increased value,the results showed that all three diagnostic AUC values were above 0.7,and the combined diagnostic AUC value was＞0.9,which was greater than each index alone,and the difference was statistically significant(P＜0.05).Statistically significant differences(P＜0.05)were found between recurrent and non-recurrent patients in terms of tumor diameter,clinical stage,surgical approach,Campanicci's radiographic grading,plain CT values before enhancement,CT values after enhancement and CT increase.The preenhanced plain CT values,postenhanced CT values and CT increase values of patients with giant cell tumor of bone were positively correlated with tumor diameter,clinical stage and Campanicci's radiographic grade(P＜0.05);tumor diameter,clinical stage,surgical method,Campanicci's radiographic grade,preenhanced plain CT values,postenhanced CT values and CT increase values were closely correlated with the clinical prognosis of patients with giant cell tumor of bone(P＜0.05).The clinical prognosis of patients with giant cell tumor was strongly correlated(P＜0.05).Conclusion The CT value of MSCT examination in patients with giant cell tumor of bone is significantly higher,which has good diagnostic efficacy in the qualitative diagnosis of giant cell tumor of bone,and can suggest postoperative recurrence if combined with tumor diameter,clinical stage and other factors for prognosis,providing a reference basis for clinical work.
Giant Cell Tumor of BoneMSCT ExaminationQualitative DiagnosisClinical Prognosis
NETL
NSTL
万方数据
维普
