To Investigate the Correlation between Collateral Circulation and Infarct Core Growth Rate in Patients with AIS Evaluated by CTP Combined with dCTA
Objective To investigate the correlation between the status of collateral circulation and the growth rate of infarct core in patients with AIS using CTP combined with dCTA.Methods A total of 62 AIS patients admitted to our hospital from August 2022 to May 2023 were included in this study.All patients underwent cranial CTP within 24 hours of onset.The total time from onset to CTP was recorded.According to the ASITN/SIR Collateral score,0-2 was defined as the poor collateral circulation group,and 3-4 was defined as the good collateral circulation group.Infarct core volume can be obtained from the original CTP data,infarct core growth rate=infarct core volume/total time from onset to CTP.The changes of infarct core growth rate under different collateral circulation status were compared.Results The infarct core volume,infarct core growth rate and rTmax in the poor collateral circulation group were higher than those in the good collateral circulation group,and the rCBF,rCBV and mismatch rate were lower than those in the good collateral circulation group,and the differences were statistically significant(P＜0.05).rCBF,rCBV and mismatch rate were positively correlated with collateral circulation score,and infarct core volume,infarct core volume growth rate and rTmax were negatively correlated with collateral circulation score,and the differences were statistically significant(P＜0.05).Conclusion Patients with poor collateral circulation may have a faster growth rate of infarct core,which can help clinicians to provide guidance for the further management of patients.
万方数据
维普
