Evaluated Value of CT Perfusion Imaging Parameters on Collateral Circulation of Acute Cerebral Infarction and Correlation with Postoperative Short-term Prognosis
Objective To explore the evaluated value of CT perfusion imaging(CTPI)parameters on collateral circulation of acute cerebral infarction(ACI)and its correlation with postoperative short-term prognosis.Methods 106 patients with ACI admitted to the hospital from January 2022 to February 2023 were selected.Digital subtraction angiography(DSA)was used as the"gold standard"for diagnosis,and the patients were divided into collateral circulation group(46 cases)and non-collateral circulation group(60 cases).CTPI examination was performed in both groups.CTPI parameters[cerebral blood volume(CBV),cerebral blood flow(CBF),mean transit time(MTT),time to peak(TTP)]were compared between the two groups of subjects,and the predictive value of CTPI parameters on ACI collateral circulation was analyzed by receiver operating characteristic(ROC)curve.The consistency of CTPI parameters in evaluating collateral circulation of acute ischemic cerebral infarction with DSA examination was compared.Pearson correlation analysis was used to analyze the correlation between CTPI parameters of patients with ACI and scores of National Institutes of Health Stroke Scale(NIHSS)and Modified Ranking Scale(mRS).Results The CBV and CBF in collateral circulation group were higher than those in non-collateral circulation group(P＜0.05),and the MTT and TTP were shorter than those in non-collateral circulation group(P＜0.05).ROC curve analysis showed that the CBV,CBF,MTT,TTP and combined detection had predictive efficiency on ACI collateral circulation(P＜0.05),and their AUCs were 0.793,0.705,0.841,0.669 and 0.879 respectively.MTT had the highest efficiency in single detection,but it was still lower than combined detection.The sensitivity,specificity,accuracy rate,positive predictive value,negative predictive value and Kappa value of the combination of CTPI parameters in the diagnosis of ACI collateral circulation were 84.78％,90.00％,87.74％,86.67％,88.52％and 0.750 respectively.NIHSS score and mRS score were lower in collateral circulation group than those in non-collateral circulation group(P＜0.05).Pearson correlation analysis found that CBV and CBF were negatively correlated with NIHSS score and mRS score(P＜0.05),but MTT and TTP were positively correlated with NIHSS score and mRS score(P＜0.05).Conclusion The CBV and CBF of ACI patients with collateral circulation are higher than those of patients without collateral circulation,and the MTT and TTP are shorter than those of patients without collateral circulation.CTPI parameters have high diagnostic efficiency on evaluating the collateral circulation of ACI,and the short-term prognosis of patients with collateral circulation is better.CBV,CBF,MTT and TTP are correlated with short-term prognosis of ACI patients.The short-term prognosis of patients can be predicted by detecting CBV,CBF,MTT and TTP.
万方数据
维普
