Cranial Imaging Characteristics of Toxic Encephalopathy Caused by Sophora Tonkinensis Gagnep
Objective To investigate the cranial imaging characteristics of patients with toxic encephalopathy caused by Sophora Tonkinensis Gagnep,and to provide a basis for clinical diagnosis.Methods The Wanfang medical database,VIP database,CNKI,Ace Base of CMA were searched from the time of the construction of the libraries to February 2023.The literatures on toxic encephalopathy caused by Sophora Tonkinensis Gagnep were extracted,and the cranial imaging characteristics were established and the data were analyzed.Results 87 patients with toxic encephalopathy were included in the study,most of which were preschooler and school aged children(54/87,62.07％).The main clinical symptoms were vertigo,gait disturbance,co nscious disturbance,torsion spasm,malaise,bulbar paralysis,etc.The main cranial imaging findings were symmetrical lesions in bilateral cerebellum and/or bilateral basal ganglia.With the increase of poisoning dose,the involved sites increased(esuch as brain stem,cerebral hemisphere).Impaired consciousness is frequently associated with bilateral basal ganglia involvement.Cranial MRI scans showed:symmetrical T1 hypointensity,T2 hyperintensity,DWI hyperintensity or isointensity,ADC hypointensity or hyperintensity.Conclusion Imaging of toxic encephalopathy caused by Sophora tonkinensis Gagnep is characterised by symmetrical lesions in the bilateral cerebellum and bilateral basal ganglia that can involve the brainstem and lobes,with the more sites of involvement more clinically severe.
Sophora Tonkinensis GagnepToxic EncephalopathyImaging Characteristics ri
万方数据
维普
