Effects of Low-concentration Contrast Agent on Radiation Dose and Incidence Rate of Contrast-induced Nephropathy in Patients with Head and Neck CTA
Objective To analyze the effects of low-concentration contrast agent on radiation dose and incidence rate of contrast-induced nephropathy(CIN)in patients with head and neck CT angiography(CTA).Methods 68 patients who underwent head and neck CTA examination in the hospital from January 2022 to December 2022 were randomly divided into low-concentration group(34 cases)and high-concentration group(34 cases).The contrast agent was 320mgl/mL and tube voltage was 100kVp in low-concentration group,and the contrast agent was 350mgl/mL and tube voltage was120kVp in high-concentration group.The differences in image subjective score and objective image quality[CT value,signal-to-noise ratio(SNR)and contrast-to-noise ratio(CNR)at each part]were compared between the two groups,and the radiation dose[CT volume dose index(CTDlvol),dose length product(DLP),effective dose(ED)]and the incidence rates of CIN and other adverse reactions were recorded in the two groups.SNR and CNRof overweight and obese people were evaluated in both groups.Results There was no statistical significant difference in the image subjective score between the two groups(P＞0.05),and the two radiologists had good consistency in the judgment of the two groups of images(P＜0.05).The CT values,SNR values and CNR values of ascending aorta,common carotid artery and middle cerebral artery in low-concentration group were higher than those in high-concentration group(P＜0.05)while the CTDlvol,DLP and ED were lower than those in high-concentration group(P＜0.05).There were no statistical differences in the adverse reactions and SNR and CNR of overweight and obese people between the two groups(P＞0.05).Conclusion 320mgl/mL iodine contrast agent and 100kVp tube voltage combined with three-dimensional adaptive iterative dose reduction algorithm reconstruction can achieve the double advantages of high image quality and low radiation dose,and it is also beneficial to reducing the risk of CIN,but it may not be suitable for overweight and obese subjects.
CTAHead and NeckContrast AgentLow-concentrationimage QualityRadiation DoseContrast-induced Nephropathy
万方数据
维普
