Clinical Characteristics,Chest CT Imaging Characteristics and Related Factors of Plastic Bronchitis in Children with MPP
Objective To analyze the clinical characteristics,chest CT imaging characteristics and related influencing factors of plastic bronchitis(PB)in children with Mycoplasma pneumoniae pneumonia(MPP).Methods A total of 206 children with MPP treated in the hospital were enrolled as the research objects between February 2019 and March 2023.According to bronchoscopy results,they were divided into PB group(n=48)and non-PB group(n=158).The clinical data,laboratory indexes,results of chest CT and bronchoscopy in both groups were retrospectively analyzed.The influencing factors of PB in MPP children were analyzed by multivariate Logistic regression analysis.Results The thermal spike,fever duration,hospitalization time,times of bronchoscopy,incidence of dyspnea and lung rales in PB group were higher than those in non-PB group(P<0.05),levels of C-reactive protein(CRP),procalcitonin(PCT),lactate dehydrogenase(LDH),creatine kinase isoenzyme(CK-MB),erythrocyte sedimentation rate(ESR)and D-dimer(D-D)were higher than those in non-PB group(P<0.05),and incidence of double-lung consolidation,pleural effusion,segmental atelectasis,bronchial mucus impaction and pleural lesions was higher than that in non-PB group(P<0.05).In PB group,there was sputum bolt block in respiratory tract under bronchoscopy,which was common in the lower right site[20.83%(10/48)]and lung lobes[29.17%(14/48)].The proportion of cases with mucosal necrosis in PB group was significantly higher than that in non-PB group(P<0.05).The results of multivariate Logistic regression analysis showed that fever duration>11d,pleural effusion,CRP>36.82mg/L and LDH>545.29U/L were important influencing factors of PB in MPP children.Conclusion There is high thermal spike,long fever duration,significant increase of CRP,LDH,CK-MB and ESR,pleural effusion and atelectasis in MPP children.Fever duration>11d,pleural effusion,CRP>36.82mg/L and LDH>545.29U/L are important influencing factors of PB in MPP children.