Effect of Body Mass Index on Survival after Cryoablation in Patients with Stage Ⅲ/ⅣNon-small Cell Lung Cancer
Objective To investigate the relationship between body mass index(BMI)and survival in patients with stage Ⅲ/Ⅳ NSCLC treated with cryoablation.Methods The clinical data of 49 patients with stageⅢ/Ⅳ primary non-small-cell lung cancer who underwent CT-guided cryoablation were retrospectively analyzed.Association between body mass index and overall survival after cryoablation(COS)were analyzed.Results Of the 49 patients,3 patients were low weight,33 cases were normal weight,13 cases were overweight,and 0 case was obese.The mean COS was 11.00 months,10.79 months,and 17.08months,respectively,in the group of low-weight,normal weight,and overweight group.The difference in COS between normal and overweight group was statistically significant,P=0.013<0.05,when the two groups were compared by LSD.Spearman's correlation analysis showed that stage(r=-0.355,P=0.015<0.05)and BMI(r=0.399,P=0.006<0.05)were correlated with survival after cryoablation.a biased correlation analysis was performed after controlling for stage,and BMI remained correlated with COS(r=0.327,P=0.028<0.05).Conclusion BMI was independently associated with survival in patients with stage Ⅲ/Ⅳ NSCLC treated with cryoablation,and patients with high BMI had longer COS.
Non-small Cell Lung CancerBody Mass IndexCryoablationComputed TomographyOverall Survival