The Effect of Chest Muscle Index Assessment Based on CT on Short-term Prognosis after Thoracoscopic Radical Resection of Esophageal Cancer
Objective To investigate the effect of preoperative chest muscle index(PMI)assessment based on CT on short-term prognosis after thoracoscopic radical resection of esophageal cancer.Methods From December 2018 to February 2022,80 patients undergoing thoracoscopic radical surgery for esophageal cancer in the Department of Thoracic and Cardiovascular Surgery of the Second People's Hospital of Anhui Province were selected as the study subjects.According to the median PMI score,the patients were divided into high PMI group and low PMI group.Gender,age,body mass index,tumor location,TNM stage,albumin and lymphocyte count were collected by electronic medical record system within 48 hours after admission.Progression-free survival(PFS)and overall survival(OS)were calculated.Nutritional risk screening 2002(NRS2002)scale was used to screen the nutritional risk of patients within 7 days after operation,and the hospitalization time and pulmonary infection during hospitalization were counted.Results There was no significant difference in gender,age,body mass index,tumor location,TNM stage and lymphocyte count between the two groups(P＞0.05).The albumin in the low PMI group was lower than that in the high PMI group,and the difference was statistically significant(P＜0.05).A total of 80 patients were followed up for 13-40 months,with a median follow-up of 27 months.A total of 16 patients died,including 5 in the high PMI group and 11 in the low PMI group.The median PFS and OS in the high PMI group were 23 months and 29 months,respectively.The PFS and OS in the low PMI group were 15 months and 24 months,respectively.The difference between the two groups was statistically significant(x2=8.100,5.049,P=0.004,0.025);COX regression analysis showed that preoperative PMI was an independent factor affecting the short-term prognosis of patients with esophageal cancer(P＜0.05).The incidence of nutritional risk,hospitalization time and pulmonary infection in the low PMI group was higher than that in the high PMI group,and the difference was statistically significant(P＜0.05).Conclusion Patients with low PMI after thoracoscopic radical resection of esophageal cancer have higher risk of short-term postoperative disease progression and death,higher nutritional risk,longer hospital stay,and higher incidence of pulmonary infection.
万方数据
维普
