ObjectiveToinvestigate the correlation between expression of ER and AR in breast cancer and preoperative MRI signs.Methods A total of 234 cases of breast cancer patients from June 2020 to March 2022 in Gansu Women's and Children's Health Hospital were collected and divided into ER and AR expression group(n=155)and non of both ER and AR expression group(n=79)according to postoperative immunohistochemistry.The single-factor correlation analysis between ER and AR expression and preoperative MRI signs was performed using Sperman and two independent samples t-test,and the statistically significant MRI signs were screened and the multi-factor Logistics correlation analysis was performed.Results There were no significant differences between AR and ER expression and tumor morphology in breast cancer(all P＞0.05),but there were significant differences with tumor body diameter,annular enhancement,tumor edge and peritumoral edema(all P＜0.05).For AR and ER expression patients in breast cancer,the tumor diameter was smaller,annular enhancement and peritumoral edema were less common.The binary Logistic regression analysis showed that:annular enhancement(OR=0.421,P=0.041),and peritumoral edema(OR=0.505,P=0.025)were the independent predictors of AR and ER expression in breast cancer.Conclusion Preoperative MRI signs have a good correlation with expression of AR and ER in breast cancer.Peritumoral edema and annular enhancementburr-like changes are rare in patients with expression of AR and ER in breast cancer,and the tumor has low biological activity and weak invasion.
关键词
乳腺癌/雌激素受体/雄激素受体/磁共振成像
Key words
Breast Cancer/Estrogen Receptor/Androgen Receptor/Magnetic Resonance Imaging
维普
万方数据