Clinical Value of Multiparametric MRI Combined with Spiral CT in Predicting Recurrence after Concurrent Chemoradiotherapy in Cr Stage Cervical Cancer
Objective To investigate the value of multi-parameter MRI combined with SCT in predicting recurrence of stage ⅢCr cervical cancer after CCRT.Methods The MRI and SCT examinations data of 70 patients with recurrence after CCRT for stage ⅢCr cervical cancer and another 66 patients without recurrence in our hospital from January 2018 to January 2020 were retrospectively analyzed.Then the value of two examinations in predicting the recurrence of patients was evaluated.Results Local puncture and follow-up showed recurrence of cervical cancer in 70 patients and non-recurrence in 66 patients.MRI parameters including minimal ADC values(ADCmin),mean ADC values(ADCmean),maximal ADC values(ADCmax),volume transfer constant(Ktrans),rate constant(Kep)and extravascular extracellular volume fraction(Ve)were significantly higher in recurrence group than in control group,and the apparent diffusion coefficient(ADC)value showed no significant difference between the two groups(P＞0.05).Using clinical diagnosis as the"gold standard",the sensitivity and specificity of multi-parameter MRI in the diagnosis of recurrence of cervical cancer were 85.71％and 89.39％respectively,while the sensitivity and specificity of SCT in the diagnosis of recurrence of cervical cancer were 55.71％and 81.82％respectively.ROC curve found that the multi-parameter MRI combined with SCT had the highest sensitivity and specificity of 94.30％and 93.30％[AUC=0.941,95％CI(0.895～0.987)].Conclusion Multi-parameter MRI is more valuable than SCT in the diagnosis of recurrence of stage ⅢCr cervical cancer after CCRT while the combination of the two can effectivelv improve the clinical diagnostic efficacy of cervical cancer recurrence.
万方数据
维普
