The Value of CT Value and CT Value Difference in Quantitative Evaluation of Fresh and Old Osteoporotic Vertebral ComDression Fractures
Objective To explore the diagnostic value of vertebral CT value and the difference of CT value between fractured vertebral body and adjacent normal vertebral body for fresh and old osteoporotic compression fractures.Methods A retrospective analysis of 384 vertebral bodies in 107 patients with osteoporosis was performed.There were 23 males and 84 females,with a median age of 73 years.MRI was used as the reference standard,including 126 fresh fracture vertebrae and 66 old fracture vertebrae.The CT values of each fractured vertebral body and adjacent normal vertebral body were measured and the CT value difference between the two was calculated.The CT values of fresh fracture and adjacent normal vertebral body,old fracture and adjacent normal vertebral body,CT values of fresh fracture and old fracture vertebral body and CT value difference were compared by independent sample t test.ROC curve was used to analyze the optimal cut-off value of CT value and CT value difference between fresh and old fracture vertebrae.Results The CT values of fresh fractures and adjacent normal vertebrae were statistically different.The CT value of fresh vertebrae was higher than that of normal vertebrae,and the average CT values were(151.74±43.25)HU and(51.67±25.31)HU,respectively.There was no significant difference in the CT value between the old fracture and the normal vertebral body.The average CT values were(59.49±27.28)HU and(53.17±25.21)HU,respectively.The difference of CT value and CT value between fresh fracture and old fracture was statistically significant.The difference of CT value was(95.61±39.80)HU and(6.32±11.35)HU,respectively.ROC curve analysis showed that the optimal cut-off value of CT value of fresh and old fractured vertebral bodies was 105.33 HU,and AUC was 0.983.The best cut-off value of CT value difference was 35.67 HU,and AUC was 0.999.The ROC curve of the combination of the two showed an AUC of 1.Conclusion Vertebral CT value and CT value difference can quantitatively evaluate fresh and old OVCF,and the diagnostic efficiency of the difference is better.The combined evaluation of the two can further improve the diagnostic confidence,and can be used as an important supplement to provide a basis for clinical diagnosis and treatment when MRI examination is limited.
万方数据
维普
