Imaging Features and Diagnostic Value of Giant Cell Tumor of Spine Bone
Objective The imaging features of giant cell tumor of spine bone were analyzed to improve the diagnosis and differential diagnosis of giant cell tumor of spine bone.Methods Imaging data of 25 cases of giant cell tumor of vertebral body and appendicular bone confirmed by clinicopathology were retrospectively analyzed.Among them,22 cases underwent DR Examination,23 cases underwent CT examination(4 cases underwent enhanced examination),25 cases underwent MR Examination(13 cases underwent enhanced examination),and 5 cases underwent systemic nuclear medicine examination(3 cases underwent local image fusion examination).Combined with the literature,the imaging features were analyzed and the rules were summarized.Results Of the 25 patients,4 were cervical,8 were thoracic,9 were lumbar,and 4 were sacral.Besides the sacral vertebra,19 cases involved both the vertebral body and the lamina,and 5 cases involved the vertebral body centered on the attachment.In DR,19 patients showed low density shadow,among which 3 patients showed"soap bubble"like change,14 patients had unilateral pedicle ring incomplete or disappeared,1 patient had bilateral disappearance,5 patients had vertebral compression fracture and 1 patient had vertebral spondylolisthesis.CT showed expansive lytic bone destruction with uneven density reduction.7 cases showed localized sclerotic edge,7 cases showed bony ridge,5 cases showed vertebral compression fracture and 1 case of vertebral detachment.MRI findings were mainly equal and low signal on T1WI,and equal,high or high,equal and low mixed signal on T2WI.Soft tissue mass was observed in 23 cases,vertebral compression fracture was observed in 5 cases,and vertebral spondylolisthesis was observed in 1 case,and vertebral body was"dumbbell"shaped in 2 cases.5 cases showed abnormal radionuclide concentration in the lesion area on whole-body bone scan,and 3 cases showed incomplete ring radionuclide concentration at the lesion edge on local image fusion.Conclusion Spinal giant cell tumor of bone has certain imaging features.Comprehensive application of multiple imaging examinations and analysis of its image manifestations can improve the diagnostic accuracy and provide reliable data for clinical use.