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脊柱骨巨细胞瘤的影像学特征及诊断价值

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目的 分析脊柱骨巨细胞瘤的影像学特征,提高对脊柱骨巨细胞瘤的诊断及鉴别诊断水平.方法 回顾性分析临床病理证实的25例脊柱椎体及附件骨巨细胞瘤的影像学资料,其中22例行DR检查,23例进行CT检查(其中4例行增强检查),25例行MR检查(其中13例行增强检查),5例行全身核医学检查(其中3例局部图像融合检查),结合文献分析其影像学特征并总结规律.结果 25例患者,发生于颈椎4例,胸椎8例(其中1例胸椎病变累及相邻2个椎体及附件),腰椎9例,骶椎4例.骶椎以外21例同时侵犯椎体及椎板,其中5例以附件为中心累及椎体.DR中19例表现为低密度影,其中3例见"皂泡"样改变,14例单侧椎弓根环不完整或消失,1例双侧消失,5例椎体压缩骨折并其中1例椎体滑脱;CT表现为膨胀性溶骨性骨质破坏,密度不均匀减低,8例病灶边缘见局限性硬化缘,7例见骨嵴;MRI表现为T1WI等、低信号为主,T2WI等、高或高、等、低混杂信号,22例见软组织肿块,5例椎体压缩骨折并其中1例椎体滑脱,其中2例椎体呈"哑铃"形改变;5例全身骨扫描表现为病变区放射性核素异常浓聚,其中3例局部图像融合表现为病灶边缘不完整环形放射性核素浓聚.结论 脊柱骨巨细胞瘤有一定影像学特征,综合应用多种影像学检查,分析其影像表现,可提高诊断正确率,为临床提供可靠的资料.
Imaging Features and Diagnostic Value of Giant Cell Tumor of Spine Bone
Objective The imaging features of giant cell tumor of spine bone were analyzed to improve the diagnosis and differential diagnosis of giant cell tumor of spine bone.Methods Imaging data of 25 cases of giant cell tumor of vertebral body and appendicular bone confirmed by clinicopathology were retrospectively analyzed.Among them,22 cases underwent DR Examination,23 cases underwent CT examination(4 cases underwent enhanced examination),25 cases underwent MR Examination(13 cases underwent enhanced examination),and 5 cases underwent systemic nuclear medicine examination(3 cases underwent local image fusion examination).Combined with the literature,the imaging features were analyzed and the rules were summarized.Results Of the 25 patients,4 were cervical,8 were thoracic,9 were lumbar,and 4 were sacral.Besides the sacral vertebra,19 cases involved both the vertebral body and the lamina,and 5 cases involved the vertebral body centered on the attachment.In DR,19 patients showed low density shadow,among which 3 patients showed"soap bubble"like change,14 patients had unilateral pedicle ring incomplete or disappeared,1 patient had bilateral disappearance,5 patients had vertebral compression fracture and 1 patient had vertebral spondylolisthesis.CT showed expansive lytic bone destruction with uneven density reduction.7 cases showed localized sclerotic edge,7 cases showed bony ridge,5 cases showed vertebral compression fracture and 1 case of vertebral detachment.MRI findings were mainly equal and low signal on T1WI,and equal,high or high,equal and low mixed signal on T2WI.Soft tissue mass was observed in 23 cases,vertebral compression fracture was observed in 5 cases,and vertebral spondylolisthesis was observed in 1 case,and vertebral body was"dumbbell"shaped in 2 cases.5 cases showed abnormal radionuclide concentration in the lesion area on whole-body bone scan,and 3 cases showed incomplete ring radionuclide concentration at the lesion edge on local image fusion.Conclusion Spinal giant cell tumor of bone has certain imaging features.Comprehensive application of multiple imaging examinations and analysis of its image manifestations can improve the diagnostic accuracy and provide reliable data for clinical use.

SpineGiant Cell Tumor Of BoneImaging Diagnosis

赵颖、陈亚玲、张斌青

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河南省洛阳正骨医院(河南省骨科医院)影像中心(河南洛阳 471000)

脊柱 骨巨细胞瘤 影像诊断

2024

中国CT和MRI杂志
北京大学深圳临床医学院 北京大学第一医院

中国CT和MRI杂志

CSTPCD
影响因子:1.578
ISSN:1672-5131
年,卷(期):2024.22(2)
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