Application of CTA/CTP Evaluation in Interventional Therapy of Ischemic Cerebrovascular Diseases
Objective To explore the application value of CT angiography(CTA)/CT perfusion(CTP)in interventional therapy of ischemic cerebrovascular diseases.Methods 200 patients with ischemic cerebrovascular diseases in our hospital were selected from January 2021 to September 2023.All patients underwent CTA examination and CTP examination after admission.The imaging data were analyzed to explore the application value of CTA and CTP in interventional therapy of ischemic cerebrovascular diseases.Results Comparison of cerebral blood volume(CBV)revealed ischemic penumbra＞healthy side＞infarction area(P＜0.05).Cerebral blood flow(CBF)was as follows:healthy side＞ischemic penumbra＞infarction area(P＜0.05).Mean transit time(MTT),time to peak(TTP)and time to maximum(Tmax)showed healthy side＜ischemic penumbra＜infarction area(P＜0.05).CTA detected left and right middle cerebral artery(MCA)occlusion or stenosis in 59 cases(29.50％)and 91 cases(45.50％),left and right internal carotid artery(ICA)occlusion in 16 cases(8.00％)and 12 cases(6.00％),and bilateral ICA stenosis in 6 cases(3.00％).The development of compensatory branch vessels was basically satisfactory in 129 cases(64.50％)and insufficient in 71 cases(35.50％),and the CTA imaging data of the remaining 16 cases(8.00％)showed no abnormality,with a sensitivity of 92.00％.The CBV and CBF of the affected side in poor prognosis group were lower than those in good prognosis group,and the MTT,TTP and Tmax were longer than those in good prognosis group,and the proportion of compensatory vascular establishment was lower than that in good prognosis group(P＜0.05).Receiver operating characteristic curve analysis showed that CBV,CBF,MTT,TTP and Tmax had certain predictive efficiency on the prognosis of interventional therapy(P＜0.05),and the areas under the curves were 0.839,0.815,0.673,0.713 and 0.710 respectively.CBV had the highest predictive efficiency,with a sensitivity of 83.20％and a specificity of 73.33％.Conclusion CTA/CTP can reflect the stenosis or occlusion of the brain and internal carotid artery,the establishment of compensatory branches,and the blood perfusion.It can provide an accurate basis for judging the reasonable timing of interventional therapy and improve the prognosis of patients.
万方数据
维普
