Clinical Value of Combination of Chest CT Pulmonary Inflammation Index,Lactic Acid and NLR in Prognosis of COVID-19 Pneumonia
Objective To analyze the chest CT images and clinical data of 2019 novel coronavirus-associated pneumonia(COVID-19)patients with different prognosis.Methods 45 patients in the survival group and 13 patients in the death group diagnosed with COVID-19 pneumonia were enrolled retrospectively.The clinical data,laboratory indicators,and chest CT PII scores were statistically analyzed.Results There were significant differences between the two groups in lymphocytes,Neutrophil to lymphocyte ratio(NLR),D-dimer,procalcitonin,C-reactive protein,albumin,oxygenation index,Lac,PII(first and after 7-14 days).Single logistic regression results showed that lymphocyte(OR 6.392),NLR(OR 0.933),oxygenation index(OR 1.011),lactic acid(OR 0.076),and the first Pll(OR 0.065)had statistical differences in the prognosis of COVID-19.Stepwise multivariate logistic regression analysis showed that Lac was an independent risk factor for death of COVID-19(P=0.025).The results of Receiver operating characteristic analysis(ROC)showed that the area under curve(AUC)of Lac,combination of PII(first time),Lac and NLR were 0.875(95％CI 0.755～0.995)and 0.895(95％CI 0.755～0.999)respectively,in predicting the prognosis of COVID-19 pneumonia.Conclusion Lactic acid is an independent risk factor for the prognosis of COVID-19.The combination of PII(first time),Lac and NLR may have a better clinical value.
COVID-19PrognosisPulmonary Inflammation Index of Chest CTNeutrophil to Lymphocyte RatioLactic Acid
万方数据
维普
