Value of CCTA Quantitative Plaque Analysis in Evaluating High-risk Plaque Progression in Elderly Patients with Coronary Heart Disease
Objective To discuss the value of coronary computed tomography angiography(CCTA)quantitative plaque analysis in evaluating high-risk plaque progression in elderly patients with coronary heart disease.Methods Ninety elderly patients with coronary heart disease who were admitted to cardiology department of the hospital from August 2020 to August 2022 were selected.All received CCTA.They were divided into high-risk group and non-high-risk group according to the nature of plaque.Patients with high-risk plaques were divided into progression group and non-progression group according to the one-year follow-up results.Plaque quantitative parameters of CCTA were compared between groups,and the predictive value of CCTA quantitative plaque analysis in high-risk plaque progression was analyzed.Results CCTA found that the incidence of high-risk plaques was 83.33％(75/90).There were 64(71.11％)cases of punctate calcified plaques and 38(42.22％)cases of low-density plaques.Compared with the non-high-risk group,RI and lipid plaque load were higher in the high-risk group(P＜0.05).CCTA-derived fractional flow reserve(FFRct)and pericoronary fat attenuation index(FAI)were lower in the high-risk group(P＜0.05).Compared with the non-progression group,total plaque volume,non-calcified plaque volume,stenosis degree,RI and lipid plaque load were greater in the progression group(P＜0.05).The minimum lumen area,FFRct and FAI were smaller in the progression group(P＜0.05).The areas under the ROC curves of total plaque volume,non-calcified plaque volume,stenosis degree,minimum lumen area,FFRct,FAI,RI,lipid plaque load,and their combination for predicting high-risk plaque progression in elderly patients with coronary heart disease were 0.807,0.801,0.788,0.756,0.763,0.768,0.775,0.806 and 0.872.Conclusion CCTA quantitative plaque analysis is of great significance for evaluating high-risk plaques and their progression in elderly patients with coronary heart disease.
万方数据
维普
