The Value of Magnetic Resonance Diffusion Weighted Imaging in Evaluating the Efficacy of Radiotherapy and Chemotherapy for Advanced Esophageal Cancer
Objective To investigate the predictive value of magnetic resonance diffusion weighted imaging in the efficacy of radiotherapy and chemotherapy for advanced esophageal cancer.Methods A total of 32 patients with advanced esophageal cancer who underwent radical chemoradiotherapy in Nanyang Central Hospital from September 2021 to December 2022 were randomly included.MRI and DWI scans were performed before and after chemoradiotherapy.According to the evaluation results of solid tumor efficacy,they were divided into remission group and non-remission group.The ADC value,maximum tumor diameter,ADC value change rate and maximum tumor diameter change rate before and after chemoradiotherapy were compared between the two groups.The t test is used on the measurement data,and the value of each parameter in evaluating the efficacy of radiotherapy and chemotherapy for advanced esophageal cancer was analyzed by ROC curve.Results A total of 32 patients with advanced esophageal cancer received chemoradiotherapy,including 25 in the remission group and 7 in the non-remission group.Before chemoradiotherapy,the ADC value and ADC change rate of the remission group were higher than those of the non-remission group,but the difference was not statistically significant(P＞0.05).After chemoradiotherapy,the ADC value of the remission group was higher than that of the non-remission group,and the maximum diameter of the tumor was smaller than that of the non-remission group(P＜0.05).The ADC values of all patients after treatment were higher than those before treatment and the difference was statistically significant(P＜0.05).ROC curve showed that when ADC value was 2.540×10-3/(mm2·s-1)after radiotherapy and chemotherapy,it was the best threshold.At this time,patients with esophageal cancer could be diagnosed as remission after radiotherapy and chemotherapy.The sensitivity was 72.0％,the specificity was 71.4％,and the area under the ROC curve was 0.791.Conclusion Magnetic resonance diffusion weighted imaging is of great value in evaluating the efficacy of radiotherapy and chemotherapy in patients with advanced esophageal cancer.The ADC value after radiotherapy and chemotherapy can accurately predict its efficacy.
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