Splenic Blood Flow Parameters Based on Energy Spectrum CT Imaging Were Used to Evaluate the Degree of Esophageal and Gastric Varices in Cirrhotic Patients with Portal Hypertension
Objective To investigate the value of splenic blood flow parameters based on energy spectrum CT imaging in evaluating the degree of esophagogastric varices(GOV)in cirrhotic patients with portal hypertension(CPH).Methods Clinical data of 80 patients with CPH(study group)were retrospectively analyzed,and 38 patients with normal liver CT during the same period were included in the control group.Parameters of abdominal enhanced CT scan based on energy spectrum CT imaging were recorded,and the value of spleen blood flow parameters based on energy spectrum CT imaging in evaluating GOV degree of CPH patients was analyzed according to the gold standard of gastroscopy results.Results Gastroscopy showed that 16 cases were grade 0,19 cases were grade 1,33 cases were grade 2,and 12 cases were grade 3.The splenic vein diameter(D-SV),actual portal vein iodine concentration(IC-S),spleen volume(V-S)and spleen iodine volume(IV-S)in control group were lower than those in study group(P＜0.05).With the increase of disease grade,V-S,IC-S,IV-S and D-SV in study group showed an increasing trend(P＜0.05).Taking grade 0 patients as control,the diagnostic AUC value of spleen blood flow combined with each parameter in GOV of CPH patients was 0.879,sensitivity was 71.25％,and specificity was 89.37％.The combined value of splenic blood flow parameters in the diagnosis of severe esophagogastric fundus varices in cirrhotic portal hypertension patients was 0.825,the sensitivity was 70.33％,and the specificity was 83.69％.Conclusion The application of energy spectrum CT detection can be combined with functional and morphological perspectives to analyze the changes of spleen hemodynamics in patients with different degrees of GOV,providing an objective basis for the early diagnosis of GOV and the evaluation of the severity of varices,which is worthy of promotion.
Energy Spectrum CT ImagingSplenic Blood Flow ParametersCirrhosis of The LiverPortal HypertensionVenae Esophagogastric FundusDegree of Curvature
万方数据
维普
