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动态对比增强磁共振成像在卵巢癌中的应用观察

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目的 探讨动态对比增强共振成像在卵巢癌中的应用效果.方法 选择2020年6月至2022年7月疑似卵巢癌患者86例为对象,所有患者均行动态对比增强共振成像检查,以病理检查结果作为"金标准",分析该方法的诊断效能;按选取位置不同确诊患者感兴趣区分为整个肿瘤、肿瘤热点及肿瘤周围组织三组.借助Tissue 4D软件包完成动态对比增强共振成像图片后处理,比较各组定量参数.结果 疑似卵巢癌患者经"金标准"检查确诊52例,确诊率为60.47%.动态对比增强磁共振检查阳性患者46例,检查准确度为83.72%(72/86)、灵敏度80.77%(42/52)、特异度为88.24%(30/34)、阳性预测值为91.30%(42/46)、阴性预测值75.00%(30/40);上皮性卵巢癌36例,卵巢交界性肿瘤16例,上皮性卵巢癌患者动态对比增强共振成像定量参数Ktrans、Ve、Kep及iAUC水平高于上皮性卵巢癌(P<0.05);卵巢癌患者肿瘤热点Ktrans、Ve、Kep及iAUC水平高于肿瘤周围组织和整个肿瘤(P<0.05).结论 动态对比增强共振成像用于卵巢癌患者中,具有较高的诊断效能,能了解组织微血管的渗透性,可间接反应肿瘤血管的生成,且监测肿瘤热点评估结果更准确.
Application Observation of Dynamic Contrast-enhanced Magnetic Resonance Imaging in Ovarian Cancer
Objectie To explore the application effect of dynamic contrast-enhanced resonance imaging in ovarian cancer.Methods 86 suspected ovarian cancer patients from June 2020 to July 2022 were selected as the study subjects,and all patients underwent dynamic contrast-enhanced magnetic resonance imaging.The pathological examination results were used as the"gold standard"to analyze the diagnostic efficacy of this method;According to the selected location,the confirmed patients are divided into three groups of interest:the entire tumor,tumor hotspots,and surrounding tissues.Complete dynamic contrast-enhanced resonance imaging image post-processing with the help of the Tissue 4D software package,and compare quantitative parameters of each group.Results 52 suspected ovarian cancer patients were diagnosed through the"gold standard"examination,with a diagnosis rate of60.47%.46 positive patients underwent dynamic contrast-enhanced magnetic resonance imaging,with an accuracy of 83.72%(72/86),sensitivity of 80.77%(42/52),specificity of88.24%(30/34),positive predictive value of 91.30%(42/46),and negative predictive value of 75.00%(30/40);There were 36 cases of epithelial ovarian cancer and 16 cases of ovarian borderline tumors.The dynamic contrast-enhanced magnetic resonance imaging quantitative parameters Ktrans,Ve,Kep,and iAUC levels in epithelial ovarian cancer patients were higher than those in epithelial ovarian cancer patients(P<0.05);The levels of tumor hotspots Ktrans,Ve,Kep,and iAUC in ovarian cancer patients were higher than those in the surrounding tissues and the entire tumor(P<0.05).Conclusion Dynamic contrast-enhanced resonance imaging has high diagnostic efficacy in ovarian cancer patients,which can understand the permeability of tissue microvessels,indirectly reflect the generation of tumor blood vessels,and monitor tumor hotspot evaluation results more accurately.

Dynamic Contrast-enhanced Resonance ImagingOophoromaPathological ExaminationDiagnostic EffectivenessQuantitative Parameters

刘荣亮、赵仁源、夏顺英

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四川省宜宾市妇幼保健计划生育服务中心放射科(四川宜宾 644000)

动态对比增强共振成像 卵巢癌 病理检查 诊断效能 定量参数

宜宾市卫生健康委医学科研项目(2021)

2021YW0036

2024

中国CT和MRI杂志
北京大学深圳临床医学院 北京大学第一医院

中国CT和MRI杂志

CSTPCD
影响因子:1.578
ISSN:1672-5131
年,卷(期):2024.22(4)
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