Evaluation Value of Magnetic Resonance T1rho Sequence and T2 Mapping in Early Diagnosis of Early Cartilage Degeneration of Knee Joint
Objective To evaluate the value of MRI T1rho sequence and T2 mapping in the early diagnosis of early cartilage degeneration of the knee.Methods A total of 110 patients with early cartilage degeneration of knee joint treated in our hospital from January 2020 to November 2022(observation group)were selected and divided into mild degeneration group and severe degeneration group according to the severity of the disease.Another 64 healthy patients who underwent physical examination in our hospital during the same period were selected as control group.All subjects were scanned with magnetic resonance T1rho sequence and T2 mapping technology,and their T2 and T1-p values were measured to explore the evaluation value of magnetic resonance T1rho sequence and T2 mapping technology in the early diagnosis of early cartilage degeneration of the knee joint.Results T2 values of lateral femur,lateral femur,lateral tibia,lateral tibia and hip bone surface in observation group were significantly higher than those in control group(P＜0.05),and T2 values of lateral femur,lateral femur,lateral tibia,lateral tibia and hip bone surface in severe degeneration subgroup were significantly higher than those in mild degeneration group(P＜0.05).The T1-p value of magnetic resonance in loading area of medial malleolus of femur,non-loading area of medial malleolus of femur,loading area of lateral malleolus of femur,non-loading area of lateral malleolus of femur,medial tibial plateau area and posterior patellar cartilage area of observation group was significantly higher than that of control group(P＜0.05).The T1-p value of magnetic resonance in the weight-bearing area of medial malleolus of femur,non-weight-bearing area of medial malleolus of femur,lateral malleolus of femur,non-weight-bearing area of lateral malleolus of femur,medial tibial plateau area and posterior patellar cartilage area of patients in severe degeneration subgroup was significantly higher than that in mild degeneration subgroup(P＜0.05).The diagnostic ROC value and specificity of MRI T1rho sequences in early diagnosis and severity assessment of knee cartilage degeneration were significantly higher than T2 mapping technique(P＜0.05),but the latter had higher sensitivity(P＜0.05).Conclusion Both T1rho and T2 mapping techniques can effectively reflect the changes of cartilage histological components in the early stage of cartilage degeneration of the knee joint,and can also provide objective evidence for the evaluation of the severity of cartilage degeneration of the knee joint.They have certain complementary value.
Magnetic Resonance T1rho SequenceT2 Mapping TechnologyKnee JointEarly Cartilage DegenerationDiagnosis
万方数据
维普
