Diagnostic Value of MRI-DWI Combined with PWI on Prognosis in Patients with Acute Cerebral Infarction
Objective To explore the diagnostic value of magnetic resonance imaging diffusion weighted imaging(MRI-DWI)combined with perfusion weighted imaging(PWI)on the prognosis in patients with acute cerebral infarction(ACI).Methods The data of 80 patients with ACI in our hospital were retrospectively analyzed.All patients underwent routine MRI sequence,DWI examination and PWI examination,and the changes in DWI detection results and apparent diffusion coefficient(ADC)value and PWI perfusion parameters[regional cerebral blood volume(rCBV),regional cerebral blood flow(rCBF),mean transit time(MTT),time to peak(TTP)]were observed.All patients received conventional treatment and were followed up for 3 months and were divided into good prognosis group and poor prognosis group according to the prognosis status.The general data and parameters of DWI and PWI of the two groups and parameters of DWI and PWI before and after treatment were compared,and the diagnostic value of DWI and PWI parameters on the prognosis of ACI was analyzed.Results The NIHSS score in poor prognosis group at admission was significantly higher than that in good prognosis group(P＜0.05),while the proportion of ischemic penumbra was significantly lower than that in good prognosis group(P＜0.05),but there were no statistically significant differences in gender,age,lesion diameter and comorbidity between the two groups(P＞0.05).The ADC,rCBV and rCBF in poor prognosis group were significantly lower than those in good prognosis group(P＜0.05),and the TTP was significantly longer than that in good prognosis group(P＜0.05).There was no statistical significance in MTT between the two groups(P＞0.05).After treatment,ADC,rCBV and rCBF were significantly increased(P＜0.05),while MTT and TTP were significantly shortened(P＜0.05).ROC curve analysis showed that the AUCs of ADC,rCBV,rCBF and TTP independently and combined diagnosis in predicting the prognosis in patients with ACI were 0.793,0.752,0.751,0.749 and 0.915 respectively.Conctusion MRI-DWI combined with PWI examination is helpful to find the early infarction lesions of ACI,and has high predictive value on the prognosis in patients with ACI,and it can assist clinical quantitative analysis and provide objective basis for the treatment of ACI.
Magnetic Resonance ImagingDiffusion-weighted imagingPerfusion Weighted ImagingAcute Cerebral InfarctionPrognosisDiagnostic value
NETL
NSTL
万方数据
维普
