CT and MRI Imaging Manifestations and Clinical Diagnosis and Treatment Value of Patients with Reversible Posterior Encephalopathy Syndrome
Objective To analyze the imaging features of computerized tomography(CT)and Magnetic resonance imaging,MRI)in patients with reversible posterior encephalopathy syndrome(PRES).And draw a risk prediction model.Methods The clinical data of 42 patients with PRES admitted in our hospital from January 2022 to August 2023 were analyzed.At the same time,40 patients with reversible cerebrovascular contraction syndrome(RCVS)admitted to our hospital and 40 patients with normal physical examination in the same period were selected as the control group.To analyze the characteristics of CT and MRI images of patients,and to analyze the diagnostic and predictive value of two kinds of examination methods for this disease.Results The results of univariate analysis showed that there were multiple flaky low CT density lesions in bilateral frontal and occipital lobes on CT,bilateral symmetry on CT,CT lesion boundary,bilateral parietal and occipital lobes on MRI,MRI basal ganglia signal,MRI frontal lobe signal,MRIT1WI lesion signal and MRIT2WI lesion signal,which were statistically different among PRES,RCVS and normal subjects(P<0.05).The results of further analysis showed that the main influencing factors of PRES patients'lesions were multiple patches of low CT density lesions in bilateral frontal,parietal and occipital lobes,symmetry of CT,boundary of CT lesions,abnormal signal in bilateral parietal and occipital lobes on MRI,abnormal signal in basal ganglia on MRI,and signal at the bottom of lesions on MRIT2WI(P<0.05).Two joint values are obtained by regression coefficient,and joint data are obtained by statistical analysis.Further ROC curve showed that the diagnostic AUC of CT and MRI were 0.884 and 0.887,and the sensitivity and specificity were 78.6%,87.5%,76.2%and 85.0%respectively.The joint prediction AUC was 0.982,and the sensitivity and specificity were 92.9%and 92.5%respectively.Conclusion CT and MRI are valuable in the diagnosis and prediction of reversible posterior encephalopathy syndrome.However,in order to avoid the limitation of single test,it is suggested to make a comprehensive evaluation by combining the symptoms of patients and other examination methods.