Imaging Findings and Clinical Features of Cerebellar Dysplastic Gangliocytoma
Objective To investigate the CT and MRI imaging features of cerebellar dysplastic gangliocytoma,and to analyze the clinical treatment,prognosis and relationship with Cowden syndrome,so as to improve the understanding and differential diagnosis of the disease.Methods The clinical and imaging datas of cerebellar dysplastic gangliocytoma confirmed by surgery and pathology were retrospectively analyzed.The location,size,imaging characteristics and enhancement of the tumor before operation were determined.Results Two of the seven patients were involved in the left cerebellar hemisphere,cerebellar vermis and pontine cerebellar binding arm,one was in the left cerebellar hemisphere and cerebellar tonsil,one was in the left cerebellar hemisphere,and three were in the right cerebellar hemisphere.Among them,one case showed obvious calcification on CT,seven cases showed laminar isointensity and low signal intensity on T1WI,and T2WI showed laminar isointensity and high signal intensity,six cases showed obvious"tabby sign"change,and five cases showed striped mild enhancement on enhanced MRI.During follow-up,two patients had tumor recurrence and one patient was diagnosed with Cowden syndrome.Conclusion The imaging findings of cerebellar dysplastic gangliocytoma are characteristic of"tabby sign",most of them show mild striated enhancement,and mostly have favourable prognosis.Comprehensive preoperative examination is helpful to make the diagnosis of Cowden syndrome.