首页|COVID-19肺炎感染对冠脉狭窄及吸烟危险性研究

COVID-19肺炎感染对冠脉狭窄及吸烟危险性研究

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目的 本研究旨在探讨COVID-19流行期间病毒性肺炎阳性以及其他危险因素对冠状动脉狭窄程度的影响.方法 选取新冠疫情放开后一个月内(2023-1-1至2023-1-31)就诊于我院行冠脉CTA证实冠脉狭窄的患者237例作为观察组和110例冠脉CTA证实冠脉无狭窄患者作为对照组,并给予所有患者行胸部CT检查,观察有无病毒性肺炎.将观察组的冠脉狭窄分成轻、中、重度三级,比较两组年龄、性别、吸烟、糖尿病、高血压、病毒性肺炎等情况,分析各种危险因素对冠脉狭窄的影响.结果 冠脉狭窄组中病毒性肺炎阳性率(31.13%)高于对照组(22.72%)(P<0.05),重度狭窄患者中肺炎的发病率要高于其他(x2=10.439,P=0.001),轻、中度狭窄无统计学意义;logistic回归分析显示,病毒性肺炎阳性不是冠脉狭窄的独立危险因素,但病毒性肺炎的阳性者冠脉重度狭窄的发生率较其他患者多2倍左右(OR值为1.897,P<0.001);进一步研究表明,病毒性肺炎阳性还会明显增加在吸烟人群中冠脉重度狭窄的发生率(OR值为6.339,P=0.003).结论 COVID-19流行期间,病毒性肺炎阳性与冠脉狭窄的发生有关,仅为冠脉重度狭窄的独立危险因素,能明显增加吸烟人群中冠脉重度狭窄的发生率.
Study on the risk of COVID-19 Pneumonia Infection and Coronary Artery Stenosis and Smoking
Objective The objective of this study was to investigate the influence of positive viral pneumonia and other risk factors on the degree of coronary artery stenosis during the COVID-19 epidemic.Methods A total of 237 patients admitted to our hospital with coronary stenosis confirmed by CTA within one month after the release of COVID-19(2023-1-1-2023-1-31)were selected as the observation group and 110 patients with no coronary stenosis confirmed by CTA were selected as the control group.All patients were given chest CT examination to observe whether there was viral pneumonia.The coronary artery stenosis in the observation group was divided into three levels:mild,moderate and severe.Age,gender,smoking,diabetes,hypertension,viral pneumonia and other conditions of the two groups were compared to analyze the influence of various risk factors on coronary artery stenosis.Results The positive rate of viral pneumonia in the coronary stenosis group(31.13%)was higher than that in the control group(22.72%)(P<0.05).The incidence of pneumonia in the severe stenosis group was higher than that in the other group(x 2=10.439,P=0.001),but there was no statistical significance in the mild and moderate stenosis.logistic regression analysis showed that positive viral pneumonia was not an independent risk factor for coronary artery stenosis,but the incidence of severe coronary artery stenosis was about 2 times higher in positive patients with viral pneumonia than in other patients(OR value was 1.897,P<0.001).Further study showed that positive viral pneumonia also significantly increased the incidence of severe coronary artery stenosis in smokers(OR 6.339,P=0.003).Conclusion During the COVID-19 epidemic,positive viral pneumonia is associated with the occurrence of coronary artery stenosis,and is an independent risk factor for severe coronary artery stenosis,and can significantly increase the incidence of severe coronary artery stenosis in smoking population.

Coronary StenosisCOViD-19Smoking

祝静雅、杨本强、佟晶、孙玉、张立波

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北部战区总医院放射诊断科(辽宁沈阳 110001)

冠脉狭窄 COVID-19 吸烟

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2020JH2/10300119

2024

中国CT和MRI杂志
北京大学深圳临床医学院 北京大学第一医院

中国CT和MRI杂志

CSTPCD
影响因子:1.578
ISSN:1672-5131
年,卷(期):2024.22(5)
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