Study on the risk of COVID-19 Pneumonia Infection and Coronary Artery Stenosis and Smoking
Objective The objective of this study was to investigate the influence of positive viral pneumonia and other risk factors on the degree of coronary artery stenosis during the COVID-19 epidemic.Methods A total of 237 patients admitted to our hospital with coronary stenosis confirmed by CTA within one month after the release of COVID-19(2023-1-1-2023-1-31)were selected as the observation group and 110 patients with no coronary stenosis confirmed by CTA were selected as the control group.All patients were given chest CT examination to observe whether there was viral pneumonia.The coronary artery stenosis in the observation group was divided into three levels:mild,moderate and severe.Age,gender,smoking,diabetes,hypertension,viral pneumonia and other conditions of the two groups were compared to analyze the influence of various risk factors on coronary artery stenosis.Results The positive rate of viral pneumonia in the coronary stenosis group(31.13%)was higher than that in the control group(22.72%)(P<0.05).The incidence of pneumonia in the severe stenosis group was higher than that in the other group(x 2=10.439,P=0.001),but there was no statistical significance in the mild and moderate stenosis.logistic regression analysis showed that positive viral pneumonia was not an independent risk factor for coronary artery stenosis,but the incidence of severe coronary artery stenosis was about 2 times higher in positive patients with viral pneumonia than in other patients(OR value was 1.897,P<0.001).Further study showed that positive viral pneumonia also significantly increased the incidence of severe coronary artery stenosis in smokers(OR 6.339,P=0.003).Conclusion During the COVID-19 epidemic,positive viral pneumonia is associated with the occurrence of coronary artery stenosis,and is an independent risk factor for severe coronary artery stenosis,and can significantly increase the incidence of severe coronary artery stenosis in smoking population.