Value Analysis of Multiparametric Magnetic Resonance Imaging Technology in Predicting Surgical Prognosis of Prostatic Cancer Patients
Objective To explore the value of multiparametric magnetic resonance imaging(Mp-MRI)technology in predicting the surgical prognosis of prostatic cancer(PCa)patients.Methods A retrospective study was conducted on 108 cases of Pca treated in hospitals from January 2016 to December 2022.According to the research purpose,all patients received routine MRI,diffusion-weighted imaging(DWI),dynamic contrast enhanced-magnetic resonance imaging(DCE-MRI)and other Mp-MRI examinations before surgery,and recorded apparent diffusion coefficient(ADC value),volume transfer constant(Ktrans),rate constant(Kep),extravascular extracellular space volume ratio(Ve)and plasma volume fraction(Vp)and other parameters,and the general clinical data and baseline examination items of the patients were counted.The recurrence and metastasis of Pca patients after surgery were used as the criteria to evaluate the prognosis,and the working characteristic curve(ROC curve)of subjects was drawn to evaluate the value of Mp-MRI parameters in predicting the prognosis of Pca patients.Results During the follow-up period,a total of 27 out of 108 Pca surgical patients experienced recurrence and metastasis,with an incidence rate of 25％.The differences in TNM staging,Gleason score,serum PSA level,ADC value,Ktrans and Ve values among patients with different prognosis were statistically significant(P＜0.05).According to Pearson correlation test,there was a negative correlation between ADC values and serum PSA in Pca patients(r＜0,P＜0.05).There was a positive correlation between Ktrans,Ve values and serum PSA(r＞0,P＜0.05).According to Logistic regression analysis,a decrease in ADC value,an increase in Ktrans and Ve values,an upregulation of serum PSA expression,a high TNM stage,and Gleason score were influencing factors for the increased risk of surgical prognosis in Pca patients(OR＞0,P＜0.05).ROC curve was drawn,and Mp-MRI parameters alone and in combination had certain predictive value in predicting the prognosis of Pca patients.Conclusion The Mp-MRI parameter is helpful in assisting in predicting the surgical prognosis of PCa patients,and the combined application of parameters can improve the predictive efficiency.
NETL
NSTL
万方数据
维普
