Diagnostic Value of Multi-parameter Magnetic Resonance Ⅵ-RADS in the Pathological Grading and Muscularity of Bladder Cancer
Objective To evaluate the significance of the multi-parameter magnetic resonance(mp-MRI)imaging method based on bladder imaging reporting and data system(Ⅵ-RADS)in bladder urothelial carcinoma(BUC).Methods The data of 48 BUC patients with pathological confirmation(a total of 49 lesions)in Chuzhou Hospital affiliated to Anhui Medical University from May 2018 to February 2022 were analyzed.According to the postoperative pathological results,the patients were divided into muscle layer invasive bladder cancer(MIBC)and non-muscle layer invasive bladder cancer(NMIBC)groups,low grade(LG)and high grade(HG)groups.The two imaging physicians reported the images of these patients according to the Ⅵ-RADS,and then the score of Ⅵ-RADS was compared with the pathological stage and grade to evaluate the diagnostic value of mp-MRI imaging method based onⅥ-RADS in MIBC and HG.Subject operating characteristic(ROC)curves were used to analyze the diagnostic efficacy of Ⅵ-RADS scores on the histopathological features of two BUC.Results Ⅵ-RADS agreement between the rat(79.60,kappa value=0.730,P＜0.001).The mp-MRI imaging method based on Ⅵ-RADS showed a significant difference between MIBC and NMIBC and LG and HG groups(Z=-4.587 and-2.871,P＜0.05).ROC curve analysis showed that the area under the curve(AUC)for diagnosed MIBC was 0.915(95％CI 0.899-90.931)for Ⅵ-RADS 3.5,yoden index 0.665,sensitivity 66.67％,specificity 99.86％,0.757(95％CI 0.730-0.783),0.379,sensitivity 77.72％,and specificity 60.13％.The Ⅵ-RADS score was higher than HG and statistically significant(Z=-2.106,P＜0.05).Conclusion The Ⅵ-RADS based mp-MRI imaging method has high diagnostic efficacy in MIBC and HG and higher diagnostic value for MIBC than HG.
Bladder CancerImaging Report and Data SystemMultiparameter Magnetic ResonanceDiagnosisPathology
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