Value of CT Texture Analysis in Preoperative Evaluation of Pathological Characteristics of Gastric Cancer Tissue
Objective To investigate the value of CT texture analysis in preoperative evaluation of pathological characteristics of gastric cancer tissue.Methods The data of 103 gastric cancer patients admitted to the hospital from March 2021 to March 2023 were analyzed retrospectively.All patients received CT examination before surgical treatment,and CT texture parameters in arterial phase and venous phase were obtained using texture analysis software.The texture parameters of patients in different TNM stages were compared,and the performance of texture parameters in gastric cancer staging was evaluated using the receiver operating characteristic(ROC)curve.Results There were no statistically significant differences in mean values between the T1-2 group and the T3-4 group in arterial phase or portal phase(P>0.05).Kurtosis and entropy of the T3-4 group were significantly higher than those of the T1-2 group,and the skewness was lower than that of the T1-2 group(P<0.05).There was no statistically significant difference in mean value or skewness between the N0 group and the N1-3 group in arterial phase or portal phase(P>0.05).Kurtosis and entropy of the N1-3 group were significantly higher than those of the N0 group(P<0.05).The AUC values of CT texture kurtosis,skewness and entropy in arterial phase for diagnosing T stage were 0.755,0.955 and 0.747(P<0.05).The AUC values of the three parameters in portal phase for diagnosing T stage were 0.959,0.871 and 0.872(P<0.05).The AUC values of CT texture kurtosis and skewness in arterial phase for diagnosing N stage were 0.899 and 0.702(P<0.05).The AUC values of CT texture kurtosis and skewness in portal phase for diagnosing N stage were 0.924 and 0.758(P<0.05).Conclusion CT texture analysis has good effects in TNM staging of gastric cancer,and can be used to guide the treatment of gastric cancer in clinical practice.