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CT纹理分析对胃癌组织病理特征的术前评估价值

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目的 探究CT纹理分析对胃癌组织病理特征的术前评估价值.方法 回顾性分析本院2021年3月~2023年3月本院收治的103例胃癌患者资料,患者在手术治疗前均接受CT检查,并采用纹理分析软件获取患者动脉以及静脉期CT纹理参数,并比较不同TNM分期患者纹理参数差异,采用受试者工作特征(ROC)曲线评估纹理参数对胃癌分期的诊断效能.结果 动脉期以及门脉期T1-2组与T3-4组平均值比较差异无统计学意义(P>0.05),但T3-4组峰度值、熵值均显著高于T1-2组,偏度值低于T1-2组(P<0.05).动脉期以及门脉期N0组与N1-3组平均值、偏度值比较差异无统计学意义(P>0.05),但N1-3组峰度值、熵值显著高于N0组(P<0.05).动脉期CT纹理峰度值、偏度值、熵值诊断T分期的AUC为0.755、0.955及0.747(P<0.05),门脉期CT纹理峰度值、偏度值、熵值诊断T分期的AUC为0.959、0.871及0.872(P<0.05).动脉期CT纹理峰度值、偏度值诊断N分期的AUC为0.899、0.702(P<0.05),门脉期CT纹理峰度值、偏度值诊断N分期的AUC为0.924、0.758(P<0.05).结论 CT纹理分析对胃癌TNM分析诊断评估效果良好,可用于临床指导胃癌患者治疗.
Value of CT Texture Analysis in Preoperative Evaluation of Pathological Characteristics of Gastric Cancer Tissue
Objective To investigate the value of CT texture analysis in preoperative evaluation of pathological characteristics of gastric cancer tissue.Methods The data of 103 gastric cancer patients admitted to the hospital from March 2021 to March 2023 were analyzed retrospectively.All patients received CT examination before surgical treatment,and CT texture parameters in arterial phase and venous phase were obtained using texture analysis software.The texture parameters of patients in different TNM stages were compared,and the performance of texture parameters in gastric cancer staging was evaluated using the receiver operating characteristic(ROC)curve.Results There were no statistically significant differences in mean values between the T1-2 group and the T3-4 group in arterial phase or portal phase(P>0.05).Kurtosis and entropy of the T3-4 group were significantly higher than those of the T1-2 group,and the skewness was lower than that of the T1-2 group(P<0.05).There was no statistically significant difference in mean value or skewness between the N0 group and the N1-3 group in arterial phase or portal phase(P>0.05).Kurtosis and entropy of the N1-3 group were significantly higher than those of the N0 group(P<0.05).The AUC values of CT texture kurtosis,skewness and entropy in arterial phase for diagnosing T stage were 0.755,0.955 and 0.747(P<0.05).The AUC values of the three parameters in portal phase for diagnosing T stage were 0.959,0.871 and 0.872(P<0.05).The AUC values of CT texture kurtosis and skewness in arterial phase for diagnosing N stage were 0.899 and 0.702(P<0.05).The AUC values of CT texture kurtosis and skewness in portal phase for diagnosing N stage were 0.924 and 0.758(P<0.05).Conclusion CT texture analysis has good effects in TNM staging of gastric cancer,and can be used to guide the treatment of gastric cancer in clinical practice.

Gastric CancerPathological CharacteristicCT Texture AnalysisPreoperative Evaluation

刘亚飞、李晓阳、孙培胜、许春苗、闫争强

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新乡医学院第一附属医院胃肠外科、减重代谢与疝外科(河南新乡 453100)

新乡医学院第一附属医院结核内科(河南新乡 453100)

河南省肿瘤医院医学影像科(河南郑州 450008)

胃癌 病理特征 CT纹理分析 术前评估

河南省医学科技攻关(联合共建)计划

LHGJ20190662

2024

中国CT和MRI杂志
北京大学深圳临床医学院 北京大学第一医院

中国CT和MRI杂志

CSTPCD
影响因子:1.578
ISSN:1672-5131
年,卷(期):2024.22(5)
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