Research for the Value of CT and DCE-MRI for Identificating Sacrococcygeal Bone Giant Cell Tumors and Chordoma
Objective To analyze and compare the DCE-MRI-TIC、CT features of sacrococcygeal chordoma and giant cell tumor of bone.Methods The CT and MRI data of 35 cases of sacrococcygeal chordoma and giant cell tumor of bone were retrospectively analyzed.All cases had pathological results.There were 21 patients with chordoma and 14 patients with giant cell tumor of bone.The course of illness ranges from 15 days to 5 years.Results All 35 patients underwent CT and DCE-MRI examinations.The tumors of 19 patients with chordoma were mostly located below the S3 vertebral body,near the midline of the spine.12 patients with giant cell tumor of bone occurred in the S2 vertebrae and above,deviating from the axial bone,and 8 of them involved the sacroiliac joint.Chordoma often shows irregular shape on CT images,with residual bone or calcium density shadows,so that the normal vertebral body shape disappears or is replaced by mass.However,giant cell tumor of bone often results in incomplete vertebral shell,but the vertebral outline is still visible.MRI images showed high or higher T2 signal shadow points and lamellar low signal nodules in chordoma lesions.Giant cell tumors of bone mostly showed equal or slightly higher signal shadows.DCE-MRI chordoma has the characteristic of strong delay,TIC curve type is mostly inflow type.However,most of the giant cell tumors of bone showed significant enhancement in the early stage,and then the contrast agent rapidly decreased and the signal decreased.The mean values of MCER and EP were significantly higher than those of chordoma group,and the TIC curve types were mostly outflow type.Conclusion CT combined with DEC-MRI is helpful for the diagnosis and differential diagnosis of sacrococcygeal chordoma and giant cell tumor of bone,and can provide a reliable image basis for clinic.
ChordomaGiant Cell Tumor of BoneCTDCE-MRITIC CurveDifferential Diagnosis